SCHEMBL3407529

SCHEMBL3407529

c1ccc(OC(c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
LTA4H P09960 3/20 0.43
KIF11 P52732 2/20 0.43
MAPK1 P28482 1/20 0.40
KCNN4 O15554 4/20 0.39
ALDH1A1 P00352 2/20 0.39
CA4 P22748 1/20 0.39
ALOX15 P16050 1/20 0.37
KCNA3 P22001 1/20 0.36
CA5A P35218 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
NR1H2 P55055 1/20 0.33
BAX Q07812 1/20 0.33
MAOA P21397 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10401090 0.94 KIF11 (0.43) TSHRLTA4HKIF11MAPK1KCNN4
SCHEMBL12847631 0.85 CA4 (0.56) LTA4HKIF11CA4
SCHEMBL28452330 0.84 PPARA (0.46) TSHRKIF11
SCHEMBL6503944 0.84 KIF11 (0.36) TSHRKIF11MAPK1KCNN4ALDH1A1
SCHEMBL8697056 0.84 KIF11 (0.36) TSHRKIF11MAPK1KCNN4ALDH1A1
SCHEMBL19949706 0.84 TSHR (0.42) TSHRKIF11MAPK1
SCHEMBL29312997 0.82 KIF11 (0.43) TSHRKIF11MAPK1
SCHEMBL2462232 0.82 KIF11 (0.36) TSHRKIF11MAPK1KCNN4ALDH1A1
SCHEMBL11230082 0.79 KIF11 (0.35) TSHRLTA4HKIF11MAPK1
SCHEMBL11230088 0.79 MAOB (0.49) LTA4HKIF11ALDH1A1CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114436781-B Preparation method of substituted phenol compound 安徽觅拓材料科技有限公司 2023-03-24 CN claimed
CN-114436781-A Preparation method of substituted phenol compound 安徽觅拓材料科技有限公司 2022-05-06 CN claimed
US-8834934-B2 Material encapsulation system HAVILAND PRODUCTS COMPANY (US) 2014-09-16 US claimed
CN-101078729-B Method for measuring high density lipoprotein cholesterol FUJI PHOTO FILM CO LTD 2012-07-18 CN claimed
US-7842485-B2 Enhanced alcohol tolerant microorganism and methods of use thereof THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2010-11-30 US claimed
WO-2007130745-A1 ENHANCED ALCOHOL TOLERANT MICROORGANISM AND METHODS OF USE THEREOF REGENTS OF THE UNIVERSITY OF COLORADO (US) 2007-11-15 WO claimed
US-20070218533-A1 Enhanced Alcohol Tolerant Microorganism and Methods of Use Thereof REGENTS OF THE UNIVERSITY OF COLORADO (US) 2007-09-20 US claimed
US-20060110464-A1 Material encapsulation system HAVILAND PRODUCTS COMPANY 2006-05-25 US claimed
EP-1596831-A2 MATERIAL INCAPSULATION SYSTEM Venture Management Alliance, LLC (US) 2005-11-23 EP claimed
WO-2004073033-A2 MATERIAL INCAPSULATION SYSTEM VENTURE MANAGEMENT ALLIANCE, LLC (US) 2004-08-26 WO claimed
CN-119604655-A Acrylic fiber treatment agent and use thereof 松本油脂制药株式会社 2025-03-11 CN disclosed
US-20240025927-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 US disclosed
CN-116535855-A High heat-resistant transparent soluble polyimide film and preparation method and application thereof 福州大学 2023-08-04 CN disclosed
US-20230200212-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 US disclosed
CN-114436781-B Preparation method of substituted phenol compound 安徽觅拓材料科技有限公司 2023-03-24 CN disclosed
US-20070218533-A1 Enhanced Alcohol Tolerant Microorganism and Methods of Use Thereof REGENTS OF THE UNIVERSITY OF COLORADO (US) 2007-09-20 US disclosed
US-20060110464-A1 Material encapsulation system HAVILAND PRODUCTS COMPANY 2006-05-25 US disclosed
EP-1596831-A2 MATERIAL INCAPSULATION SYSTEM Venture Management Alliance, LLC (US) 2005-11-23 EP disclosed
WO-2004073033-A2 MATERIAL INCAPSULATION SYSTEM VENTURE MANAGEMENT ALLIANCE, LLC (US) 2004-08-26 WO disclosed
US-4346187-A AND ORGANIC BROMINE COMPOUND BORG-WARNER CHEMICALS, INC. (US) 1982-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230200212-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, SIRT2, OCIAD1 TSHR 1862/4885LTA4H 2576/4885KIF11 4262/4885
US-20240025927-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 TSHR 3948/4885LTA4H 735/4885KIF11 1633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.