Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401090 | 0.84 | KIF11 (0.43) | KIF11MAPK1TSHRALDH1A1KCNN4 | |
| SCHEMBL3407529 | 0.84 | TSHR (0.43) | KIF11MAPK1TSHRALDH1A1KCNN4 | |
| SCHEMBL3645414 | 0.79 | TSHR (0.39) | KIF11MAPK1TSHRALDH1A1KCNN4 | |
| SCHEMBL11419604 | 0.79 | MAPK1 (0.50) | MAPK1TSHRALDH1A1KCNN4ALOX15 | |
| SCHEMBL3095108 | 0.79 | TSHR (0.39) | MAPK1TSHRALDH1A1KCNN4 | |
| SCHEMBL3841441 | 0.75 | TSHR (0.31) | TSHRALDH1A1 | |
| SCHEMBL3849553 | 0.75 | ALDH1A1 (0.31) | TSHRALDH1A1 | |
| SCHEMBL28452330 | 0.74 | PPARA (0.46) | KIF11TSHR | |
| SCHEMBL19949706 | 0.74 | TSHR (0.42) | KIF11MAPK1TSHR | |
| SCHEMBL8697056 | 0.74 | KIF11 (0.36) | KIF11MAPK1TSHRALDH1A1KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908996-B2 | Compounds and method for preparing 3-methylcephams | IMPERIAL COLLEGE OF LONDON (GB) | 2005-06-21 | — | — | US | disclosed |
| US-20040106790-A1 | Novel compounds and method for preparing 3-methylcephams | COOPER CONSULTING | 2004-06-03 | — | — | US | disclosed |
| US-6683176-B2 | FOR USE IN PRODUCING AMINO ACID DERIVATIVE ANTIBIOTICS | COOPER CONSULTING | 2004-01-27 | — | — | US | disclosed |
| EP-1183262-A4 | INTERMEDIATES FOR AND SYNTHESIS OF 3-METHYLENE CEPHAMS | COOPER CONSULTING INC (US) | 2003-04-09 | — | — | EP | disclosed |
| EP-1183262-A1 | INTERMEDIATES FOR AND SYNTHESIS OF 3-METHYLENE CEPHAMS | Cooper Consulting Inc. (US) | 2002-03-06 | — | — | EP | disclosed |
| WO-2001060828-A1 | INTERMEDIATES FOR AND SYNTHESIS OF 3-METHYLENE CEPHAMS | COOPER CONSULTING INC. (US) | 2001-08-23 | — | — | WO | disclosed |
| US-4618610-A | Triazine derivatives, and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-21 | — | — | US | disclosed |
| EP-0123254-A1 | Triazine derivatives, processes for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-31 | — | — | EP | disclosed |
| EP-0019401-B1 | PROCESS FOR PREPARING ENAMINE DERIVATIVES, COMPOUNDS SO PRODUCED AND PROCESS FOR PREPARING A 3-HYDROXY-CEPHALOSPORIN | Lilly Industries Limited (GB) | 1984-03-21 | — | — | EP | disclosed |
| EP-0011370-B1 | PROCESS FOR PREPARING 2-CHLOROSULFINYL-AZETIDINONES | ELI LILLY AND COMPANY (US) | 1982-04-28 | — | — | EP | disclosed |
| EP-0019401-A1 | Process for preparing enamine derivatives, compounds so produced and process for preparing a 3-hydroxy-cephalosporin | Lilly Industries Limited (GB) | 1980-11-26 | — | — | EP | disclosed |
| EP-0011370-A1 | Process for preparing 2-chlorosulfinyl-azetidinones | ELI LILLY AND COMPANY (US) | 1980-05-28 | — | — | EP | disclosed |
| US-4176231-A | Process for preparing 3-exomethylenecepham sulfoxides | LILLY INDUSTRIES LIMITED (GB) | 1979-11-27 | — | — | US | disclosed |
| US-4159266-A | AZETIDINONE SULFINIC ACID DERIVATIVES | ELI LILLY AND COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4159272-A | Process for 2-chlorosulfinylazetidin-4-ones | ELI LILLY AND COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4052387-A | METHOD OF PREPARATION OF 3-METHYLENECEPHAMS | ELI LILLY AND COMPANY (US) | 1977-10-04 | — | — | US | disclosed |
| US-4048163-A | Process for preparation of 7-alkoxy-3-chloromethylcephems | ELI LILLY AND COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
| US-4048160-A | Process for preparation of 7-alkoxy-3-bromomethylcephems | ELI LILLY AND COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
| US-4042585-A | Process for preparation of 3-halomethylcephems | ELI LILLY AND COMPANY (US) | 1977-08-16 | — | — | US | disclosed |
| US-4038275-A | PROCESS FOR PREPARATION OF 3-HYDROXYMETHYLCEPHEMS | ELI LILLY AND COMPANY (US) | 1977-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106790-A1 | Novel compounds and method for preparing 3-methylcephams | DHPS, FDPS, COASY | KIF11 4431/4885MAPK1 4269/4885TSHR 4070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.