Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3409134 | 1.00 | GPR84 (0.34) | GPR84FFAR1FFAR4PTPN1CAMK2A | |
| SCHEMBL5942917 | 1.00 | GPR84 (0.34) | GPR84FFAR1FFAR4PTPN1CAMK2A | |
| SCHEMBL2223572 | 0.93 | PTPN1 (0.33) | GPR84FFAR1FFAR4PTPN1CAMK2A | |
| SCHEMBL5146478 | 0.93 | PTPN1 (0.33) | GPR84FFAR1FFAR4PTPN1CAMK2A | |
| SCHEMBL5148636 | 0.93 | PTPN1 (0.33) | GPR84FFAR1FFAR4PTPN1CAMK2A | |
| SCHEMBL6326530 | 0.84 | THRB (0.32) | — | |
| SCHEMBL6331659 | 0.84 | THRB (0.32) | — | |
| SCHEMBL5774423 | 0.84 | THRB (0.32) | — | |
| SCHEMBL25224563 | 0.82 | FOLH1 (0.34) | — | |
| SCHEMBL7549777 | 0.82 | PLA2G2C (0.47) | GPR84FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2226325-A1 | PROCESS FOR PRODUCTION OF 4-(SUBSTITUTED PHENYL)HEXAHYDROPYRIDOÝ2,1-C¨Ý1,4¨OXAZIN-6-ONE | Eisai R&D Management Co., Ltd. (JP) | 2010-09-08 | — | — | EP | disclosed |