Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 7/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3062374 | 0.74 | PKM (0.38) | HSD17B10 | |
| SCHEMBL17768786 | 0.70 | — | — | |
| SCHEMBL17768785 | 0.67 | — | — | |
| SCHEMBL16510089 | 0.66 | BRD4 (0.34) | BRD4P2RX7 | |
| SCHEMBL27699806 | 0.65 | DPP4 (0.40) | BRD4KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL13844412 | 0.64 | BRD4 (0.37) | BRD4P2RX7 | |
| SCHEMBL17305900 | 0.63 | EGLN1 (0.48) | FDPSKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL17996825 | 0.63 | EGLN1 (0.48) | FDPSKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL4063363 | 0.63 | FDPS (0.48) | FDPSKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL7154948 | 0.63 | FDPS (0.48) | FDPSKMT2AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368342-B3 | BENZIMIDAZOLE AND PYRIDYLIMIDAZOLE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | NEUROGEN CORP (US) | 2010-12-01 | — | — | EP | disclosed |