Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA6 | P23280 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL3278776 | 1.00 | NFKB1 (0.40) | NFKB1TSHRALDH1A1CA12CA6 | |
| Ethylenediamine SCHEMBL987032 | 1.00 | NFKB1 (0.40) | NFKB1TSHRALDH1A1CA12CA6 | |
| Ethylenediamine SCHEMBL379188 | 1.00 | NFKB1 (0.40) | NFKB1TSHRALDH1A1CA12CA6 | |
| Ethylenediamine SCHEMBL4656515 | 1.00 | NFKB1 (0.40) | NFKB1TSHRALDH1A1CA12CA6 | |
| Ethylenediamine SCHEMBL5694570 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL4074999 | 1.00 | NFKB1 (0.40) | NFKB1TSHRALDH1A1CA12CA6 | |
| Ethylenediamine SCHEMBL4077319 | 1.00 | NFKB1 (0.40) | NFKB1TSHRALDH1A1CA12CA6 | |
| Ethylenediamine SCHEMBL1690184 | 1.00 | NFKB1 (0.40) | NFKB1TSHRALDH1A1CA12CA6 | |
| Ethylenediamine SCHEMBL11560258 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL986011 | 1.00 | NFKB1 (0.40) | NFKB1TSHRALDH1A1CA12CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9340723-B2 | Catalyzed polyamine sulfide scavengers and methods of use in subterranean treatment fluids | HALLIBURTON ENERGY SERVICES, INC. (US) | 2016-05-17 | — | — | US | claimed |
| EP-2262856-B1 | HYDROGEN SULFIDE SCAVENGERS AND METHODS FOR REMOVING HYDROGEN SULFIDE FROM ASPHALT | GEN ELECTRIC (US) | 2015-04-08 | — | — | EP | claimed |
| US-20150000918-A1 | CATALYZED POLYAMINE SULFIDE SCAVENGERS AND METHODS OF USE IN SUBTERRANEAN TREATMENT FLUIDS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2015-01-01 | — | — | US | claimed |
| WO-2014209722-A1 | CATALYZED POLYAMINE SULFIDE SCAVENGERS AND METHODS OF USE IN SUBTERRANEAN TREATMENT FLUIDS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2014-12-31 | — | — | WO | claimed |
| EP-2262856-A1 | HYDROGEN SULFIDE SCAVENGERS AND METHODS FOR REMOVING HYDROGEN SULFIDE FROM ASPHALT | General Electric Company (US) | 2010-12-22 | — | — | EP | claimed |
| WO-2009120419-A1 | HYDROGEN SULFIDE SCAVENGERS AND METHODS FOR REMOVING HYDROGEN SULFIDE FROM ASPHALT | GENERAL ELECTRIC COMPANY (US) | 2009-10-01 | — | — | WO | claimed |
| US-20090242461-A1 | HYDROGEN SULFIDE SCAVENGERS AND METHODS FOR REMOVING HYDROGEN SULFIDE FROM ASPHALT | GENERAL ELECTRIC COMPANY | 2009-10-01 | — | — | US | claimed |
| US-10400160-B2 | Crosslinked polymer-coated proppant | HALLIBURTON ENERGY SERVICES, INC. (US) | 2019-09-03 | — | — | US | disclosed |
| US-20180215996-A1 | Crosslinked Polymer-Coated Proppant | HALLIBURTON ENERGY SERVICES, INC. (US) | 2018-08-02 | — | — | US | disclosed |
| WO-2017052515-A1 | CROSSLINKED POLYMER-COATED PROPPANT | HALLIBURTON ENERGY SERVICES, INC. (US) | 2017-03-30 | — | — | WO | disclosed |
| US-9340723-B2 | Catalyzed polyamine sulfide scavengers and methods of use in subterranean treatment fluids | HALLIBURTON ENERGY SERVICES, INC. (US) | 2016-05-17 | — | — | US | disclosed |
| EP-2262856-B1 | HYDROGEN SULFIDE SCAVENGERS AND METHODS FOR REMOVING HYDROGEN SULFIDE FROM ASPHALT | GEN ELECTRIC (US) | 2015-04-08 | — | — | EP | disclosed |
| US-20150000918-A1 | CATALYZED POLYAMINE SULFIDE SCAVENGERS AND METHODS OF USE IN SUBTERRANEAN TREATMENT FLUIDS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2015-01-01 | — | — | US | disclosed |
| WO-2014209722-A1 | CATALYZED POLYAMINE SULFIDE SCAVENGERS AND METHODS OF USE IN SUBTERRANEAN TREATMENT FLUIDS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2014-12-31 | — | — | WO | disclosed |
| EP-2262856-A1 | HYDROGEN SULFIDE SCAVENGERS AND METHODS FOR REMOVING HYDROGEN SULFIDE FROM ASPHALT | General Electric Company (US) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009120419-A1 | HYDROGEN SULFIDE SCAVENGERS AND METHODS FOR REMOVING HYDROGEN SULFIDE FROM ASPHALT | GENERAL ELECTRIC COMPANY (US) | 2009-10-01 | — | — | WO | disclosed |
| US-20090242461-A1 | HYDROGEN SULFIDE SCAVENGERS AND METHODS FOR REMOVING HYDROGEN SULFIDE FROM ASPHALT | GENERAL ELECTRIC COMPANY | 2009-10-01 | — | — | US | disclosed |