Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA6 | P23280 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL3278776 | 1.00 | NFKB1 (0.40) | NFKB1TSHRALDH1A1CA12CA6 | |
| Ethylenediamine SCHEMBL987032 | 1.00 | NFKB1 (0.40) | NFKB1TSHRALDH1A1CA12CA6 | |
| Ethylenediamine SCHEMBL4656515 | 1.00 | NFKB1 (0.40) | NFKB1TSHRALDH1A1CA12CA6 | |
| Ethylenediamine SCHEMBL5694570 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL4074999 | 1.00 | NFKB1 (0.40) | NFKB1TSHRALDH1A1CA12CA6 | |
| Ethylenediamine SCHEMBL4077319 | 1.00 | NFKB1 (0.40) | NFKB1TSHRALDH1A1CA12CA6 | |
| Ethylenediamine SCHEMBL1690184 | 1.00 | NFKB1 (0.40) | NFKB1TSHRALDH1A1CA12CA6 | |
| Ethylenediamine SCHEMBL11560258 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL986011 | 1.00 | NFKB1 (0.40) | NFKB1TSHRALDH1A1CA12CA6 | |
| Ethylenediamine SCHEMBL3408067 | 1.00 | NFKB1 (0.40) | NFKB1TSHRALDH1A1CA12CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 442 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114164423-B | Chromium-free passivation solution and preparation method and application thereof | 广东达志化学科技有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-118307576-A | 1, 2-Dihydroxymethyl ortho-carborane and preparation method and application thereof | 四川大学 | 2024-07-09 | — | — | CN | claimed |
| EP-3720920-B1 | IONIC LIQUID BASED WELL ASPHALTENE INHIBITORS AND METHODS OF USING THE SAME | BAKER HUGHES HOLDINGS LLC (US) | 2024-01-24 | — | — | EP | claimed |
| CN-117264114-A | Preparation method of phosphorus-free environment-friendly efficient scale inhibitor | 佛山市栢豪环保科技有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-116589905-A | Corrosion-resistant structure and preparation method thereof | 安徽泽众安全科技有限公司 | 2023-08-15 | — | — | CN | claimed |
| US-11676737-B2 | Encapsulation composition for storage or confinement of waste which is toxic to health and/or the environment | POLYNT COMPOSITES FRANCE (FR) | 2023-06-13 | — | — | US | claimed |
| WO-2023084214-A1 | MATERIALS AND METHODS TO ENHANCE MINERAL SCALE DISSOLUTION RATES | SWELLFIX UK LIMITED (GB) | 2023-05-19 | — | — | WO | claimed |
| CN-114471155-A | Graphene oxide-based nanofiltration membrane as well as preparation method and application thereof | 南京工业大学 | 2022-05-13 | — | — | CN | claimed |
| CN-108602047-B | Carbon dioxide sorbents for air quality control | 巴斯夫公司 | 2022-05-03 | — | — | CN | claimed |
| US-11229897-B2 | Carbon dioxide sorbents for air quality control | BASF CORPORATION (US) | 2022-01-25 | — | — | US | claimed |
| EP-1302489-A1 | Cure accelerator system for phenolic resins | GEORGIA-PACIFIC CORPORATION (US) | 2003-04-16 | — | — | EP | claimed |
| US-6201095-B1 | DIALKOXYETHANAL-MELAMINE OR ACETYLENEUREA RESIN LOW IN COLOR MADE BY ADDING LOW AMOUNTS OF FORMALDEHYDE TO THE REACTANTS BEFORE ACIDIFICATION AND HEATING; COATED SUBSTRATES; DIMETHOXYETHANAL (DME) | OMNOVA SOLUTIONS INC. | 2001-03-13 | — | — | US | claimed |
| EP-1065227-A2 | Color improvement of dimethoxyethanal-melamine resins | Clariant (France) S.A. (FR) | 2001-01-03 | — | — | EP | claimed |
| US-5739260-A | REACTION PRODUCT OF MELAMINE AND/OR GLYCOLURIL WITH DIALKOXYETHANAL, POLYOL, HYDROPHOBIC MODIFIER; WATER RESISTANT, FORMALDEHYDE-FREE | SEQUA CHEMICALS, INC. (US) | 1998-04-14 | — | — | US | claimed |
| US-5468262-A | Reaction product of phenol aldehyde, amine condensate and succinic anhydride bearing polyolefin | TEXACO INC. (US) | 1995-11-21 | — | — | US | claimed |
| EP-0623652-A2 | Flexibilized polyepoxide resins | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1994-11-09 | — | — | EP | claimed |
| US-5334654-A | Incorporating an aliphatic, aliphatic ether or ester component having monofunctional reactivity with an amine hydrogen and an amine curative having 3 to 5 epoxide reactive hydrogen atoms | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1994-08-02 | — | — | US | claimed |
| EP-0263852-A1 | PRODUCTION OF POLYESTER FABRICS RESEMBLING WOOL | Burlington Industries, Inc. (US) | 1988-04-20 | — | — | EP | claimed |
| WO-1987005641-A1 | PRODUCTION OF POLYESTER FABRICS RESEMBLING WOOL | BURLINGTON INDUSTRIES, INC. (US) | 1987-09-24 | — | — | WO | claimed |
| US-4688605-A | Reinforced hose structure | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1987-08-25 | — | — | US | claimed |