SCHEMBL3408445

SCHEMBL3408445

O=C1c2ccccc2C(=O)N1c1ccc(Oc2ccc(N3C(=O)c4ccccc4C3=O)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.66
MEN1 O00255 5/20 0.62
NR1H3 Q13133 2/20 0.60
MGLL Q99685 1/20 0.58
BRD4 O60885 1/20 0.57
SCN2A Q99250 3/20 0.56
CA9 Q16790 3/20 0.56
CA12 O43570 2/20 0.56
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
PPARD Q03181 1/20 0.53
PPARA Q07869 1/20 0.53
GAA P10253 1/20 0.51
RAB9A P51151 1/20 0.51
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13302880 0.96 MGLL (0.65) KMT2AMEN1NR1H3MGLLBRD4
SCHEMBL21107869 0.93 KMT2A (0.63) KMT2AMEN1NR1H3MGLLBRD4
SCHEMBL10475108 0.91 KMT2A (0.57) KMT2AMEN1NR1H3MGLLBRD4
SCHEMBL10709583 0.89 BRD4 (0.64) KMT2AMEN1NR1H3MGLLBRD4
SCHEMBL4649471 0.87 KMT2A (0.78) KMT2AMEN1NR1H3SCN2ACA9
SCHEMBL22627090 0.87 KMT2A (0.56) KMT2AMEN1NR1H3MGLLBRD4
SCHEMBL18874610 0.87 KMT2A (0.56) KMT2AMEN1NR1H3MGLLBRD4
SCHEMBL17272758 0.86 BRD4 (0.73) KMT2AMEN1MGLLBRD4GAA
SCHEMBL13323537 0.85 KMT2A (0.65) KMT2AMEN1NR1H3BRD4KDM4E
SCHEMBL19689370 0.85 BRD4 (0.72) KMT2AMEN1NR1H3MGLLBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4517315-A Production of a film-like or fibrous structure of an aromatic polyester TEIJIN LIMITED (JP) 1985-05-14 US claimed
US-8211963-B2 Method of purifying a polymer SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-07-03 US disclosed
US-8211963-B2 Method of purifying a polymer SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-07-03 US disclosed
US-8158702-B2 Method of purifying a polymer SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-04-17 US disclosed
US-8158702-B2 Method of purifying a polymer SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-04-17 US disclosed
US-7999024-B2 Method of purifying a polymer SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-08-16 US disclosed
US-7999024-B2 Method of purifying a polymer SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-08-16 US disclosed
WO-2009002779-A2 METHOD OF PURIFYING A POLYMER SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-12-31 WO disclosed
EP-0156966-B1 WHOLLY AROMATIC POLYESTER COMPOSITION AND PROCESS FOR PRODUCING IT TEIJIN LIMITED (JP) 1988-10-19 EP disclosed
EP-0070539-B1 PROCESS FOR PRODUCING A FILM-LIKE AND FIBROUS ARTICLE OF A WHOLLY AROMATIC POLYESTER TEIJIN LIMITED (JP) 1987-07-01 EP disclosed
EP-0091669-B1 PROCESS FOR PRODUCING POROUS, FILM-LIKE OR FIBROUS STRUCTURE OF AROMATIC POLYESTER TEIJIN LIMITED (JP) 1986-10-01 EP disclosed
EP-0057387-B1 PRODUCTION OF A FILM-LIKE OR FIBROUS STRUCTURE OF AN AROMATIC POLYESTER TEIJIN LIMITED (JP) 1986-05-07 EP disclosed
EP-0156966-A1 Wholly aromatic polyester composition and process for producing it TEIJIN LIMITED (JP) 1985-10-09 EP disclosed
US-4517315-A Production of a film-like or fibrous structure of an aromatic polyester TEIJIN LIMITED (JP) 1985-05-14 US disclosed
US-4419308-A SOLVENT EXTRACTION OF IMIDE OR ISOCYANURATE TEIJIN LIMITED (JP) 1983-12-06 US disclosed
US-4416839-A Wholly aromatic polyester composition, process for production thereof, and production therefrom of a film-like or fibrous article of a wholly aromatic polyester TEIJIN LIMITED (JP) 1983-11-22 US disclosed
EP-0091669-A2 Process for producing porous, film-like or fibrous structure of aromatic polyester TEIJIN LIMITED (JP) 1983-10-19 EP disclosed
EP-0070539-A1 Process for producing a film-like and fibrous article of a wholly aromatic polyester TEIJIN LIMITED (JP) 1983-01-26 EP disclosed
EP-0057387-A2 Production of a film-like or fibrous structure of an aromatic polyester TEIJIN LIMITED (JP) 1982-08-11 EP disclosed