Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL11808126 | 0.89 | GLRA1 (0.40) | SLC6A2SLC6A4BLMSLC6A3MEN1 | |
| Ammonia Solution, Strong SCHEMBL5586232 | 0.86 | SLC6A2 (0.34) | SLC6A2SLC6A4BLMSLC6A3MEN1 | |
| SCHEMBL847206 | 0.71 | LMNA (0.39) | MEN1TSHRCYP2C19KMT2A | |
| SCHEMBL10886922 | 0.70 | ALDH1A1 (0.35) | SLC6A2SLC6A4BLMSLC6A3MEN1 | |
| SCHEMBL11842033 | 0.70 | HTR2A (0.33) | SLC6A2SLC6A4BLMSLC6A3MEN1 | |
| Nitrilotriacetic Acid SCHEMBL28090386 | 0.68 | TDP1 (0.52) | SLC6A2SLC6A4BLMSLC6A3MEN1 | |
| SCHEMBL10615501 | 0.67 | SLC6A2 (0.35) | SLC6A2SLC6A4BLMSLC6A3MEN1 | |
| SCHEMBL18047819 | 0.66 | SLC6A2 (0.34) | SLC6A2SLC6A4BLMSLC6A3MEN1 | |
| Cadaverine Tartrate SCHEMBL1834853 | 0.65 | TSHR (0.59) | SLC6A2BLMTSHRNFKB1 | |
| Cadaverine Tartrate SCHEMBL1833811 | 0.65 | TSHR (0.59) | SLC6A2BLMTSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063988-A1 | GERMICIDAL TOPICAL COMPOSITIONS | RECKITT & COLMAN (OVERSEAS) LIMITED (GB) | 2010-06-10 | — | — | WO | disclosed |