⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14844598 | 0.83 | NOS2 (0.32) | — | |
| SCHEMBL3415236 | 0.77 | — | — | |
| SCHEMBL3410508 | 0.77 | PDE3B (0.31) | — | |
| SCHEMBL294353 | 0.77 | NOS3 (0.30) | — | |
| SCHEMBL857493 | 0.72 | TAAR1 (0.41) | — | |
| SCHEMBL467233 | 0.70 | — | — | |
| SCHEMBL855800 | 0.70 | TAAR1 (0.34) | — | |
| SCHEMBL2067325 | 0.70 | NQO1 (0.31) | — | |
| SCHEMBL857085 | 0.69 | TAAR1 (0.39) | — | |
| SCHEMBL3859834 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3148984-B1 | PROCESS FOR THE PREPARATION OF 5-FLUORO-1H-PYRAZOLES STARTING FROM HEXAFLUOROPROPENE | BAYER ANIMAL HEALTH GMBH (DE) | 2019-07-24 | — | — | EP | disclosed |
| EP-3183237-B1 | PROCESS FOR THE PREPARATION OF 5-FLUORO-1H-PYRAZOLES STARTING FROM HEXAFLUOROPROPENE | BAYER ANIMAL HEALTH GMBH (DE) | 2019-07-24 | — | — | EP | disclosed |
| US-10059673-B2 | Process for the preparation of 5-fluoro-1H-pyrazoles starting from hexafluoropropene | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-08-28 | — | — | US | disclosed |
| US-9957256-B2 | Process for the preparation of 5-fluoro-1H-pyrazoles starting from hexafluoropropene | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-05-01 | — | — | US | disclosed |
| US-20170233348-A1 | Process for the preparation of 5-fluoro-1H-pyrazoles starting from hexafluoropropene | ELANCO ANIMAL HEALTH GMBH (DE) | 2017-08-17 | — | — | US | disclosed |
| US-20170190690-A1 | Process for the preparation of 5-fluoro-1H-pyrazoles starting from hexafluoropropene | ELANCO ANIMAL HEALTH GMBH (DE) | 2017-07-06 | — | — | US | disclosed |
| EP-3183237-A1 | PROCESS FOR THE PREPARATION OF 5-FLUORO-1H-PYRAZOLES STARTING FROM HEXAFLUOROPROPENE | Bayer CropScience Aktiengesellschaft (DE) | 2017-06-28 | — | — | EP | disclosed |
| EP-3148984-A1 | PROCESS FOR THE PREPARATION OF 5-FLUORO-1H-PYRAZOLES STARTING FROM HEXAFLUOROPROPENE | Bayer CropScience Aktiengesellschaft (DE) | 2017-04-05 | — | — | EP | disclosed |
| WO-2016026789-A1 | PROCESS FOR THE PREPARATION OF 5-FLUORO-1H-PYRAZOLES STARTING FROM HEXAFLUOROPROPENE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-02-25 | — | — | WO | disclosed |
| WO-2015181139-A1 | PROCESS FOR THE PREPARATION OF 5-FLUORO-1H-PYRAZOLES STARTING FROM HEXAFLUOROPROPENE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2015-12-03 | — | — | WO | disclosed |
| EP-2763966-A1 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES | Syngenta Participations AG (CH) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013050261-A1 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-04-11 | — | — | WO | disclosed |
| EP-2262794-A1 | SULFONAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDE | BASF SE (DE) | 2010-12-22 | — | — | EP | disclosed |
| US-20100317516-A1 | Sulfonamide Compounds And Their Use As Fungicide | BASF SE (DE) | 2010-12-16 | — | — | US | disclosed |
| WO-2009103650-A1 | SULFONAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDE | BASF SE (DE) | 2009-08-27 | — | — | WO | disclosed |