Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3401213 | 0.83 | TSHR (0.48) | TSHRL3MBTL1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4164891 | 0.83 | RAB9A (0.50) | TSHRL3MBTL1LMNASMN1; SMN2RAB9A | |
| SCHEMBL29733653 | 0.81 | TSHR (1.00) | TSHRLMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL28154099 | 0.81 | TSHR (0.68) | TSHRL3MBTL1LMNASMN1; SMN2RAB9A | |
| SCHEMBL3403751 | 0.81 | TSHR (0.68) | TSHRL3MBTL1LMNASMN1; SMN2BCHE | |
| SCHEMBL3396223 | 0.81 | TSHR (1.00) | TSHRLMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2952697 | 0.81 | TSHR (0.69) | TSHRL3MBTL1LMNASMN1; SMN2RAB9A | |
| Iodomethane SCHEMBL27798273 | 0.80 | TSHR (0.91) | TSHRLMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL16230884 | 0.80 | TSHR (0.46) | TSHRL3MBTL1LMNASMN1; SMN2RAB9A | |
| SCHEMBL26653746 | 0.80 | HSD17B10 (0.54) | TSHRL3MBTL1LMNASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273775-B2 | Non-steroidal brassinosteroid mimetic | VIB VZW (BE) | 2012-09-25 | — | — | US | claimed |
| EP-2086322-B1 | NON-STEROIDAL BRASSINOSTEROID MIMETIC | VIB VZW (BE) | 2010-12-01 | — | — | EP | claimed |
| US-20100152253-A1 | NON-STEROIDAL BRASSINOSTEROID MIMETIC | VIB VZW (BE) | 2010-06-17 | — | — | US | claimed |
| EP-2086322-A1 | NON-STEROIDAL BRASSINOSTEROID MIMETIC | VIB VZW (BE) | 2009-08-12 | — | — | EP | claimed |
| WO-2008049729-A1 | NON-STEROIDAL BRASSINOSTEROID MIMETIC | VIB VZW (BE) | 2008-05-02 | — | — | WO | claimed |
| US-8642510-B2 | Inhibitors for brassinosteroid signalling | GMI-Gregor Mendel-Institut fuer Molekulare Pflanzenbiologie GmbH (AT) | 2014-02-04 | — | — | US | disclosed |
| US-8273775-B2 | Non-steroidal brassinosteroid mimetic | VIB VZW (BE) | 2012-09-25 | — | — | US | disclosed |
| EP-2247576-B1 | INHIBITORS FOR BRASSINOSTEROID SIGNALLING | GMI GREGOR MENDEL INST FUER MOLEKULARE PFLANZENBIOLOGIE GMBH (AT) | 2012-08-08 | — | — | EP | disclosed |
| US-20100317526-A1 | Inhibitors for Brassinosteroid Signalling | GMI-GREGOR-MENDEL-INSTITUT FUER MOLEKULARE PFLANZENBIOLOGIE GMBH (AT) | 2010-12-16 | — | — | US | disclosed |
| EP-2086322-B1 | NON-STEROIDAL BRASSINOSTEROID MIMETIC | VIB VZW (BE) | 2010-12-01 | — | — | EP | disclosed |
| US-20100152253-A1 | NON-STEROIDAL BRASSINOSTEROID MIMETIC | VIB VZW (BE) | 2010-06-17 | — | — | US | disclosed |
| EP-2098510-A1 | Inhibitors for brassinosteroid signalling | GMI - Gregor-Mendel-Institut für Molekulare Pflanzenbiologie GmbH (AT) | 2009-09-09 | — | — | EP | disclosed |
| EP-2086322-A1 | NON-STEROIDAL BRASSINOSTEROID MIMETIC | VIB VZW (BE) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008049729-A1 | NON-STEROIDAL BRASSINOSTEROID MIMETIC | VIB VZW (BE) | 2008-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317526-A1 | Inhibitors for Brassinosteroid Signalling | HRH4, HRH3, INSR | TSHR 238/4885L3MBTL1 2049/4885LMNA 4276/4885 |
| US-20100152253-A1 | NON-STEROIDAL BRASSINOSTEROID MIMETIC | BRI3BP, BRD1, NR1I2 | TSHR 842/4885L3MBTL1 738/4885LMNA 4172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.