Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1967499 | 0.92 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAHPGDKDM4E | |
| SCHEMBL1967501 | 0.92 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAHPGDKDM4E | |
| SCHEMBL740361 | 0.74 | ADORA3 (0.49) | ALDH1A1RAB9ANPSR1MAPTLMNA | |
| SCHEMBL740362 | 0.74 | ADORA3 (0.49) | ALDH1A1RAB9ANPSR1MAPTLMNA | |
| SCHEMBL14523934 | 0.73 | ERBB2 (0.50) | RAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL5758996 | 0.72 | CYP4F2 (0.42) | ALDH1A1MAPTHPGDKDM4EKMT2A | |
| SCHEMBL5763596 | 0.72 | FFAR1 (0.53) | — | |
| SCHEMBL5763599 | 0.72 | FFAR1 (0.53) | — | |
| SCHEMBL5758992 | 0.72 | CYP4F2 (0.42) | ALDH1A1MAPTHPGDKDM4EKMT2A | |
| SCHEMBL5761110 | 0.72 | CYP4F2 (0.43) | ALDH1A1MAPTHPGDKDM4EGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027236-A2 | FUSED HETEROCYCLIC COMPOUND | LG LIFE SCIENCES LTD. (KR) | 2010-03-11 | — | — | WO | disclosed |