Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2865990 | 0.88 | MAPT (0.38) | LMNATP53POLBRAB9AMAPT | |
| SCHEMBL2864054 | 0.88 | MAPT (0.44) | MAPTWNT3ACYP3A4 | |
| SCHEMBL2863564 | 0.85 | EPHX2 (0.42) | RAB9AMAPTNPC1 | |
| SCHEMBL2866776 | 0.83 | CA2 (0.40) | LMNATP53MAPTWNT3A | |
| SCHEMBL2862871 | 0.83 | HDAC1 (0.36) | LMNATP53POLBRAB9AMAPT | |
| SCHEMBL2859503 | 0.83 | ALDH1A1 (0.41) | POLBRAB9ANPC1 | |
| SCHEMBL2867706 | 0.82 | EPHX2 (0.42) | LMNAPOLBRAB9AMAPTNPC1 | |
| SCHEMBL2860683 | 0.82 | MAPT (0.44) | LMNATP53MAPTWNT3A | |
| SCHEMBL2867433 | 0.81 | SCN9A (0.41) | LMNAMAPTWNT3ACYP3A4 | |
| SCHEMBL2860311 | 0.81 | EPHX2 (0.41) | POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370260-B1 | AZOLES AS MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2010-11-24 | — | — | EP | claimed |