Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27785354 | 0.78 | ALOX5 (0.46) | POLBL3MBTL1ALOX5HRH3EPHX2 | |
| SCHEMBL1502093 | 0.76 | ALDH1A1 (0.52) | POLBL3MBTL1ALOX5HRH3EPHX2 | |
| SCHEMBL20300505 | 0.76 | ALDH1A1 (0.50) | POLBL3MBTL1ALOX5HRH3EPHX2 | |
| SCHEMBL30056243 | 0.74 | ALDH1A1 (0.56) | ALOX5HRH3 | |
| SCHEMBL30598426 | 0.69 | ALOX5 (0.41) | POLBL3MBTL1ALOX5EPHX2LIPE | |
| SCHEMBL18426160 | 0.69 | HSD17B10 (0.45) | — | |
| SCHEMBL18426159 | 0.69 | HSD17B10 (0.45) | — | |
| SCHEMBL1713090 | 0.69 | ALOX5 (0.42) | POLBALOX5EPHX2HTR2CAKR1C3 | |
| SCHEMBL20300338 | 0.68 | MEN1 (0.53) | POLBL3MBTL1AKR1C3 | |
| SCHEMBL485135 | 0.68 | ALOX5 (0.45) | POLBL3MBTL1ALOX5EPHX2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2256114-B1 | AMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | DAINIPPON SUMITOMO PHARMA CO (JP) | 2014-06-25 | — | — | EP | disclosed |
| EP-2256114-A1 | AMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2010-12-01 | — | — | EP | disclosed |