Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3409710 | 0.83 | HCRTR1 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL2930537 | 0.82 | TSHR (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL3415640 | 0.82 | TSHR (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL2927637 | 0.80 | RAB9A (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL3415876 | 0.80 | CDK4 (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL2925297 | 0.80 | CDK4 (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL2925182 | 0.80 | POLB (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL2930333 | 0.79 | SMN1; SMN2 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL3412070 | 0.79 | SMN1; SMN2 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL2931896 | 0.78 | HCRTR2 (0.44) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185512-B1 | TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-12-29 | — | — | EP | claimed |
| EP-2185512-B1 | TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-12-29 | — | — | EP | disclosed |