Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3409706 | 0.83 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL2930541 | 0.82 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL3415643 | 0.82 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL2927639 | 0.81 | PARP1 (0.35) | HCRTR1HCRTR2 | |
| SCHEMBL3415880 | 0.81 | CDK4 (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL2925299 | 0.81 | CDK4 (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL2925184 | 0.80 | POLB (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL3412075 | 0.80 | HCRTR1 (0.37) | HCRTR1HCRTR2 | |
| SCHEMBL2930336 | 0.80 | HCRTR1 (0.37) | HCRTR1HCRTR2 | |
| SCHEMBL2925288 | 0.80 | HCRTR1 (0.46) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185512-B1 | TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-12-29 | — | — | EP | claimed |
| EP-2185512-B1 | TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-12-29 | — | — | EP | disclosed |