Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.37 |
| ▸ | CTH | P32929 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861075 | 0.86 | EPHX2 (0.41) | MLYCDPDE3BPDE3AP2RY12EPHX2 | |
| SCHEMBL2865664 | 0.85 | EPHX2 (0.42) | MLYCDEPHX2 | |
| SCHEMBL2857704 | 0.84 | PDE3B (0.37) | MLYCDPDE3BPDE3AP2RY12LTB4R | |
| SCHEMBL2869509 | 0.84 | MLYCD (0.37) | MLYCDPDE3BPDE3AP2RY12L3MBTL1 | |
| SCHEMBL2859557 | 0.84 | PDE3B (0.38) | MLYCDPDE3BPDE3AP2RY12CYSLTR2 | |
| SCHEMBL2866243 | 0.83 | PDE3B (0.39) | MLYCDPDE3BPDE3AP2RY12AGTR1 | |
| SCHEMBL2870239 | 0.83 | EPHX2 (0.41) | MLYCDPDE3BPDE3AP2RY12EPHX2 | |
| SCHEMBL2856847 | 0.82 | PDE3B (0.35) | MLYCDPDE3BPDE3AP2RY12LTB4R | |
| SCHEMBL2863990 | 0.82 | MLYCD (0.35) | MLYCDPDE3BPDE3AP2RY12EPHX2 | |
| SCHEMBL3402147 | 0.82 | MLYCD (0.39) | MLYCDPDE3BPDE3AP2RY12CTH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370260-B1 | AZOLES AS MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2010-11-24 | — | — | EP | claimed |