Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8298781 | 0.85 | MAPT (0.39) | MAPTNPC1RAB9ASMN1; SMN2PPARA | |
| SCHEMBL2077416 | 0.81 | APP (0.39) | MAPTNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL2870138 | 0.81 | MAPT (0.51) | MAPTNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL3405108 | 0.81 | ATM (0.38) | MAPTSMN1; SMN2PPARAALDH1A1CASP3 | |
| SCHEMBL2865968 | 0.80 | MAPT (0.47) | MAPTNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL2869556 | 0.80 | MAPT (0.40) | MAPTNPC1RAB9ASMN1; SMN2PPARA | |
| SCHEMBL2082283 | 0.79 | APP (0.40) | MAPTAPPINSR | |
| SCHEMBL2082285 | 0.79 | APP (0.40) | MAPTAPPINSR | |
| SCHEMBL2855117 | 0.79 | CA2 (0.40) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL13262428 | 0.78 | ALDH1A1 (0.37) | MAPTNPC1RAB9ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370260-B1 | AZOLES AS MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2010-11-24 | — | — | EP | claimed |