Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804029 | 0.87 | TTR (0.36) | ALDH1A1L3MBTL1TTRHPGDSMN1; SMN2 | |
| SCHEMBL28783867 | 0.83 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1TTRHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3633618 | 0.79 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL20710992 | 0.77 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1HPGDSMN1; SMN2HTT | |
| SCHEMBL28526096 | 0.77 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1HPGDSMN1; SMN2ERN1 | |
| SCHEMBL4868031 | 0.76 | CA1 (0.41) | ALDH1A1L3MBTL1HPGDSMN1; SMN2HTT | |
| SCHEMBL28987609 | 0.73 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1HPGDSMN1; SMN2HTT | |
| SCHEMBL8533780 | 0.72 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1TTRHPGDSMN1; SMN2 | |
| SCHEMBL10490593 | 0.71 | TDP1 (0.38) | L3MBTL1SMN1; SMN2HTTERN1TDP1 | |
| SCHEMBL10490625 | 0.71 | TDP1 (0.57) | ALDH1A1TTRHPGDSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257559-A1 | SYNTHESIS OF CYCLIC CARBONATES | University Of Newcastle-Upon Tyne (GB) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009109765-A1 | SYNTHESIS OF CYCLIC CARBONATES | UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2009-09-11 | — | — | WO | disclosed |