SCHEMBL28987609

SCHEMBL28987609

Cc1cc(CCl)ccc1C=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.43
TSHR P16473 1/20 0.43
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.40
PKM P14618 1/20 0.40
CYP2C19 P33261 4/20 0.40
CYP3A4 P08684 2/20 0.40
KDM4E B2RXH2 2/20 0.40
HIF1A Q16665 1/20 0.40
CYP1A2 P05177 3/20 0.37
CYP2D6 P10635 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
GRIA1 P42261 1/20 0.36
GRIA2 P42262 1/20 0.36
GRIA3 P42263 1/20 0.36
GRIA4 P48058 1/20 0.36
TYR P14679 1/20 0.35
SMN1; SMN2 Q16637 4/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2704056 0.82 ALDH1A1 (0.45) ALDH1A1TSHRRAB9ANPC1PKM
SCHEMBL29467223 0.80 KDM4E (0.36) ALDH1A1CYP2C19CYP3A4KDM4EHIF1A
SCHEMBL30216932 0.80 ALDH1A1 (0.43) ALDH1A1TSHRRAB9ANPC1PKM
SCHEMBL809404 0.80 KDM4E (0.36) ALDH1A1CYP2C19CYP3A4KDM4EHIF1A
SCHEMBL13177068 0.80 ALDH1A1 (0.43) ALDH1A1TSHRRAB9ANPC1PKM
SCHEMBL23202425 0.80 ALDH1A1 (0.43) ALDH1A1TSHRRAB9ANPC1PKM
SCHEMBL21151467 0.80 ALDH1A1 (0.43) ALDH1A1TSHRRAB9ANPC1PKM
SCHEMBL10239020 0.78 ALDH1A1 (0.42) ALDH1A1TSHRRAB9ANPC1PKM
SCHEMBL31056330 0.78 ALDH1A1 (0.42) ALDH1A1TSHRRAB9ANPC1PKM
SCHEMBL10490593 0.78 TDP1 (0.38) TSHRTDP1SMN1; SMN2MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115819195-A Preparation method of pterostilbene 三原润禾生物科技有限公司 2023-03-21 CN disclosed