Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.33 |
| ▸ | TGFBR2 | P37173 | 3/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | GLP1R | P43220 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3072695 | 0.88 | MAPT (0.40) | MAPTCYP11B2CYP17A1TGFBR1TGFBR2 | |
| SCHEMBL3061362 | 0.83 | MAPT (0.43) | MAPTCYP17A1TGFBR1TGFBR2ALOX5AP | |
| SCHEMBL3062225 | 0.82 | HDAC1 (0.35) | MAPTALOX5APENPP2 | |
| SCHEMBL13547841 | 0.80 | CYP11B2 (0.34) | CYP11B2CYP17A1CYP1A2ENPP2 | |
| SCHEMBL3061416 | 0.80 | RPS6KA5 (0.43) | MAPTCYP11B2TGFBR1ALOX5AP | |
| SCHEMBL3060407 | 0.78 | RPS6KA5 (0.37) | MAPTTGFBR1 | |
| SCHEMBL3049560 | 0.77 | TP53 (0.36) | MAPTTGFBR1TGFBR2 | |
| SCHEMBL3059564 | 0.77 | MAPT (0.36) | MAPTTGFBR1TGFBR2 | |
| SCHEMBL3067378 | 0.77 | MAPT (0.36) | MAPTCYP17A1TGFBR1TGFBR2ALOX5AP | |
| SCHEMBL3068284 | 0.76 | RAB9A (0.39) | MAPTCYP1A2TGFBR1GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368342-B3 | BENZIMIDAZOLE AND PYRIDYLIMIDAZOLE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | NEUROGEN CORP (US) | 2010-12-01 | — | — | EP | claimed |