Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.53 |
| ▸ | KDM5A | P29375 | 3/20 | 0.51 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PAM | P19021 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3412676 | 0.98 | DGKA (0.52) | DGKADNM1KDM5APHF8KDM4C | |
| SCHEMBL3415894 | 0.88 | DNM1 (0.49) | DGKADNM1LMNAPAMALDH1A1 | |
| SCHEMBL62055 | 0.87 | DGKA (0.67) | DGKALMNAPAMALDH1A1MAPT | |
| SCHEMBL4621082 | 0.87 | DGKA (0.67) | DGKALMNAPAMALDH1A1MAPT | |
| SCHEMBL8584840 | 0.87 | DGKA (0.67) | DGKALMNAPAMALDH1A1MAPT | |
| SCHEMBL21647233 | 0.87 | DGKA (0.67) | DGKALMNAPAMALDH1A1MAPT | |
| SCHEMBL152597 | 0.87 | DGKA (0.67) | DGKALMNAPAMALDH1A1MAPT | |
| SCHEMBL15527970 | 0.87 | DGKA (0.67) | DGKALMNAPAMALDH1A1MAPT | |
| SCHEMBL5189388 | 0.87 | DGKA (0.67) | DGKALMNAPAMALDH1A1MAPT | |
| SCHEMBL20529845 | 0.87 | DGKA (0.67) | DGKALMNAPAMALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265617-A1 | SOLVENTS | Bioniqs Limited (GB) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009034329-A1 | SOLVENTS | BIONIQS LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |