Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10519638 | 0.87 | TDP1 (0.56) | TDP1ALDH1A1KMT2AKEAP1FFAR1 | |
| SCHEMBL466545 | 0.79 | TDP1 (0.63) | TDP1ALDH1A1KMT2AKEAP1FFAR1 | |
| SCHEMBL28968155 | 0.78 | TDP1 (0.68) | TDP1ALDH1A1KMT2AKEAP1FFAR1 | |
| SCHEMBL6279310 | 0.77 | TDP1 (0.61) | TDP1ALDH1A1KMT2AKEAP1FFAR1 | |
| SCHEMBL29067576 | 0.77 | TDP1 (0.56) | TDP1ALDH1A1KMT2AKEAP1FFAR1 | |
| Acetone SCHEMBL16013121 | 0.75 | TDP1 (0.63) | TDP1ALDH1A1KMT2AKEAP1FFAR1 | |
| Methyl 3-Phenylpropanoate SCHEMBL17748824 | 0.75 | TDP1 (0.63) | TDP1ALDH1A1KMT2AKEAP1FFAR1 | |
| SCHEMBL7212141 | 0.75 | PTGS2 (0.53) | TDP1ALDH1A1KMT2AKEAP1FFAR1 | |
| Methyl 3-Phenylpropanoate SCHEMBL168711 | 0.74 | TDP1 (0.68) | TDP1ALDH1A1KMT2AKEAP1FFAR1 | |
| SCHEMBL1739439 | 0.74 | TDP1 (0.73) | TDP1ALDH1A1KMT2AKEAP1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268925-B2 | Graft copolymer and compositions thereof | LUBRIZOL LIMITED (GB) | 2012-09-18 | — | — | US | disclosed |
| US-20100152339-A1 | Graft Copolymer And Compositions Thereof | LUBRIZOL LIMITED (GB) | 2010-06-17 | — | — | US | disclosed |
| EP-2150333-A1 | GRAFT COPOLYMER AND COMPOSITIONS THEREOF | Lubrizol Limited (GB) | 2010-02-10 | — | — | EP | disclosed |
| WO-2008145613-A1 | GRAFT COPOLYMER AND COMPOSITIONS THEREOF | LUBRIZOL LIMITED (GB) | 2008-12-04 | — | — | WO | disclosed |