Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565000 | 0.84 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3CYP2A6CHRNA7 | |
| SCHEMBL984538 | 0.73 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CHRNA7ACHE | |
| SCHEMBL28775974 | 0.73 | KDM4E (0.39) | DRD2MAPT | |
| SCHEMBL4553663 | 0.72 | KDM4E (0.40) | SLC6A2SLC6A4CHRNA7KCNH2CHRM1 | |
| SCHEMBL28563678 | 0.72 | HSP90AA1 (0.43) | SLC6A2SLC6A4SLC6A3CHRNA7 | |
| SCHEMBL14961253 | 0.70 | CHRNB2 (0.49) | CHRNA7 | |
| SCHEMBL18394286 | 0.70 | PDE4B (0.37) | HTR4 | |
| SCHEMBL14571687 | 0.70 | SLC6A4 (0.53) | SLC6A2SLC6A4SLC6A3KCNH2CHRM1 | |
| SCHEMBL3408790 | 0.69 | HPGD (0.41) | MAPT | |
| SCHEMBL1126544 | 0.68 | DRD2 (0.38) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114878-B1 | 5-(HETEROCYCLYL)ALKYL-N-(ARYLSULFONYL)INDOLE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LTD (IN) | 2010-12-15 | — | — | EP | disclosed |
| EP-2114878-A1 | 5-(HETEROCYCLYL)ALKYL-N-(ARYLSULFONYL)INDOLE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | Suven Life Sciences Limited (IN) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008084492-A1 | 5-(HETEROCYCLYL)ALKYL-N-(ARYLSULFONYL)INDOLE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2008-07-17 | — | — | WO | disclosed |