Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | AGPAT2 | O15120 | 3/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 4/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20383160 | 0.82 | CYP3A4 (0.56) | IDO1CYP3A4AGPAT2MAP4K4S100A4 | |
| SCHEMBL4430967 | 0.79 | IDO1 (0.39) | IDO1CYP3A4AGPAT2MAP4K4S100A4 | |
| SCHEMBL3412251 | 0.76 | IDO1 (0.39) | IDO1CYP3A4AGPAT2MAP4K4S100A4 | |
| SCHEMBL4426433 | 0.76 | HTR2B (0.36) | IDO1CYP3A4RAPGEF4 | |
| SCHEMBL13176724 | 0.74 | CYP3A4 (0.48) | IDO1CYP3A4AGPAT2MAP4K4S100A4 | |
| SCHEMBL3410828 | 0.73 | ALDH1A1 (0.37) | RAPGEF4KDM4EPOLBCYP2A6LMNA | |
| SCHEMBL5086316 | 0.73 | ALKBH3 (0.35) | L3MBTL1POLBLMNA | |
| SCHEMBL16574105 | 0.72 | CYP3A4 (0.46) | IDO1CYP3A4AGPAT2MAP4K4S100A4 | |
| SCHEMBL16574096 | 0.71 | CYP3A4 (0.45) | IDO1CYP3A4AGPAT2MAP4K4S100A4 | |
| SCHEMBL16574095 | 0.71 | CYP3A4 (0.45) | IDO1CYP3A4AGPAT2MAP4K4S100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260032-A2 | FUNGICIDAL HETERCYCLIC COMPOUNDS | E. I. du Pont de Nemours and Company (US) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009094445-A2 | FUNGICIDAL HETERCYCLIC COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-30 | — | — | WO | disclosed |