Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | SELP | P16109 | 2/20 | 0.36 |
| ▸ | SELPLG | Q14242 | 1/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3412308 | 0.93 | ALDH1A1 (0.49) | ALDH1A1HPGDHSD17B10LTB4RLTB4R2 | |
| SCHEMBL1627498 | 0.88 | CYP4F2 (0.40) | NR1H2NR1H3CYP4F2CYP4A11PPARA | |
| SCHEMBL1627522 | 0.88 | ALDH1A1 (0.54) | ALDH1A1HPGDHSD17B10LTB4RLTB4R2 | |
| SCHEMBL1627500 | 0.83 | DUT (0.40) | ALDH1A1CYP4F2CYP4A11PPARA | |
| SCHEMBL1247083 | 0.81 | CYP4F2 (0.37) | CYP4F2CYP4A11PPARAPPARG | |
| SCHEMBL9320820 | 0.81 | PTGS1 (0.43) | ALDH1A1HPGDHSD17B10NR1H2NR1H3 | |
| SCHEMBL28266847 | 0.79 | CYP4F2 (0.42) | ALDH1A1NR1H2NR1H3CYP4F2CYP4A11 | |
| SCHEMBL17398452 | 0.78 | IDO1 (0.47) | — | |
| SCHEMBL21068770 | 0.77 | DUT (0.37) | CYP4F2CYP4A11PPARAPPARG | |
| SCHEMBL17760802 | 0.76 | IDO1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257315-A2 | CONTRAST AGENTS FOR APPLICATIONS INCLUDING PERFUSION IMAGING | Lantheus Medical Imaging, Inc. (US) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009110984-A2 | CONTRAST AGENTS FOR APPLICATIONS INCLUDING PERFUSION IMAGING | LANTHEUS MEDICAL IMAGING, INC. (US) | 2009-09-11 | — | — | WO | disclosed |