Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3412111 | 0.85 | MAPK14 (0.33) | MAPK14 | |
| SCHEMBL253756 | 0.84 | MEN1 (0.36) | MAPK14 | |
| SCHEMBL3409340 | 0.84 | MAPK14 (0.34) | MAPK14 | |
| SCHEMBL246806 | 0.66 | PIK3CG (0.40) | — | |
| SCHEMBL933581 | 0.62 | NOS3 (0.40) | — | |
| SCHEMBL17229785 | 0.58 | MAPK14 (0.48) | MAPK14 | |
| SCHEMBL19182951 | 0.57 | MAPK14 (0.40) | MAPK14 | |
| SCHEMBL23950805 | 0.57 | SCN5A (0.50) | MAPK14 | |
| SCHEMBL11914746 | 0.57 | MAPK14 (0.58) | MAPK14 | |
| SCHEMBL20376169 | 0.57 | MAPK14 (0.46) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003338-A1 | COMBINATION OF A cMET INHIBITOR AND AN ANTIBODY TO HGF AND/OR cMET | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-01-05 | — | — | WO | disclosed |