Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3412095 | 0.86 | IKBKB (0.47) | IKBKBLIMK1MAPTKDM4EALDH1A1 | |
| SCHEMBL3407525 | 0.86 | LIMK1 (0.45) | IKBKBLIMK1MAPTKDM4EALDH1A1 | |
| SCHEMBL3408796 | 0.84 | IKBKB (0.43) | IKBKBLIMK1MAPTKDM4EALDH1A1 | |
| SCHEMBL1176582 | 0.84 | IKBKB (0.61) | IKBKBLIMK1MAPTKDM4EALDH1A1 | |
| SCHEMBL3406906 | 0.83 | MAPT (0.45) | IKBKBLIMK1MAPTKDM4EALDH1A1 | |
| SCHEMBL3414147 | 0.83 | LIMK1 (0.42) | IKBKBLIMK1MAPTKDM4EALDH1A1 | |
| SCHEMBL3408735 | 0.82 | IKBKB (0.42) | IKBKBLIMK1MAPTKDM4EALDH1A1 | |
| SCHEMBL3411093 | 0.81 | IKBKB (0.34) | IKBKBLIMK1ALDH1A1MEN1KMT2A | |
| SCHEMBL3409501 | 0.77 | IKBKB (0.44) | IKBKBLIMK1MAPTKDM4EALDH1A1 | |
| SCHEMBL5732361 | 0.74 | LIMK1 (0.50) | IKBKBLIMK1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260044-A2 | THIENOPYRIMIDINES | Merck Patent GmbH (DE) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009124653-A2 | THIENOPYRIMIDINES | MERCK PATENT GMBH (DE) | 2009-10-15 | — | — | WO | disclosed |