SCHEMBL3413635

SCHEMBL3413635

CCNCCC[Si](OCC)(OCC)OC(C)N

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.34
MEN1 O00255 1/20 0.34
GLA P06280 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP1A2 P05177 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28124853 0.89 CA12 (0.34) MEN1KMT2A
SCHEMBL3631277 0.83 CYP2C19 (0.34) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL28098649 0.83 CYP2C19 (0.34) CYP2C19MEN1GLAKMT2ACYP1A2
Methylamine SCHEMBL11311742 0.82 CYP2C19 (0.42) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL270457 0.82 CYP2C19 (0.46) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL5049085 0.80 OPRM1 (0.37)
Ammonia Solution, Strong SCHEMBL7647790 0.80 CYP2C19 (0.44) CYP2C19MEN1GLAKMT2ACYP1A2
Diethylamine SCHEMBL7638457 0.80 CYP2C19 (0.44) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL27497971 0.79
SCHEMBL21359747 0.78 CYP2C19 (0.48) CYP2C19MEN1GLAKMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7189417-B2 Aqueous dispersion of amine-terminated silica particles having a narrowly controlled size range capable of coupling with an agent for diagnostic imaging, drug delivery or gene therapy THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2007-03-13 US claimed
US-20240274848-A1 FLUORINATED IONOMERS, POLYMER ELECTROLYTE MEMBRANES, FUEL CELLS, AND METHODS COLORADO SCHOOL OF MINES 2024-08-15 US disclosed
WO-2022256669-A1 FLUORINATED IONOMERS, POLYMER ELECTROLYTE MEMBRANES, FUEL CELLS, AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-12-08 WO disclosed
US-9240287-B2 Immobilized heteropoly acids and the use of the same electrode stabilization and enhancement COLORADO SCHOOL OF MINES (US) 2016-01-19 US disclosed
US-8993707-B2 Aqueous epoxy and organo-substituted branched organopolysiloxane emulsions WACKER CHEMICAL CORPORATION (US) 2015-03-31 US disclosed
US-20140234750-A1 IMMOBILIZED HETEROPOLY ACIDS AND THE USE OF THE SAME FOR ELECTRODE STABILIZATION AND ENHANCEMENT COLORADO SCHOOL OF MINES (US) 2014-08-21 US disclosed
US-20140058012-A1 Aqueous Epoxy and Organo-Substituted Branched Organopolysiloxane Emulsions WACKER CHEMICAL CORPORATION (US) 2014-02-27 US disclosed
US-8524131-B2 Laminate and method for making laminate NIKE, INC. (US) 2013-09-03 US disclosed
US-20100193992-A1 LAMINATE AND METHOD FOR MAKING LAMINATE NIKE, INC. (US) 2010-08-05 US disclosed