Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.56 |
| ▸ | MAOB | P27338 | 6/20 | 0.56 |
| ▸ | ACHE | P22303 | 5/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3415288 | 1.00 | MAOA (0.56) | MAOAMAOBACHEBCHEADRA2B | |
| SCHEMBL23125482 | 0.89 | MAOA (0.52) | MAOAMAOBACHEBCHE | |
| SCHEMBL23125497 | 0.89 | MAOA (0.52) | MAOAMAOBACHEBCHE | |
| SCHEMBL15113941 | 0.87 | MAOA (0.50) | MAOAMAOBACHEBCHE | |
| SCHEMBL15113801 | 0.87 | MAOA (0.50) | MAOAMAOBACHEBCHE | |
| SCHEMBL23125504 | 0.87 | MAOA (0.50) | MAOAMAOBACHEBCHE | |
| SCHEMBL24199408 | 0.84 | MAOA (0.52) | MAOAMAOBACHEBCHE | |
| SCHEMBL3378409 | 0.84 | MAOA (0.56) | MAOAMAOBACHEBCHEADRA2B | |
| SCHEMBL3378411 | 0.84 | MAOA (0.56) | MAOAMAOBACHEBCHEADRA2B | |
| SCHEMBL22186273 | 0.83 | MAOA (0.55) | MAOAMAOBACHEBCHEADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2181980-A1 | A process for the preparation of (R)-1-aminoindanes | Chemo Ibérica, S.A. (ES) | 2010-05-05 | — | — | EP | disclosed |