Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.56 |
| ▸ | MAOB | P27338 | 6/20 | 0.56 |
| ▸ | ACHE | P22303 | 6/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3378409 | 1.00 | MAOA (0.56) | MAOAMAOBACHEBCHEADRA2B | |
| SCHEMBL12171101 | 0.93 | MAOA (0.48) | MAOAMAOBACHE | |
| SCHEMBL3299930 | 0.85 | ACHE (0.49) | MAOAMAOBACHEBCHE | |
| SCHEMBL3300396 | 0.85 | ACHE (0.49) | MAOAMAOBACHEBCHE | |
| SCHEMBL12450286 | 0.84 | ACHE (0.41) | MAOAMAOBACHEBCHE | |
| SCHEMBL22186248 | 0.84 | MAOA (0.52) | MAOAMAOBACHEBCHEADRA2B | |
| SCHEMBL5899449 | 0.84 | ACHE (0.48) | MAOAMAOBACHEBCHE | |
| SCHEMBL3415286 | 0.84 | MAOA (0.56) | MAOAMAOBACHEBCHEADRA2B | |
| SCHEMBL3415288 | 0.84 | MAOA (0.56) | MAOAMAOBACHEBCHEADRA2B | |
| SCHEMBL3938891 | 0.83 | MAOA (0.40) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010049379-A1 | A PROCESS FOR THE PREPARATION OF (R)-I -AMINOINDANES | CHEMO IBÉRICA, S.A. (ES) | 2010-05-06 | — | — | WO | disclosed |
| WO-2010049379-A1 | A PROCESS FOR THE PREPARATION OF (R)-I -AMINOINDANES | CHEMO IBÉRICA, S.A. (ES) | 2010-05-06 | — | — | WO | disclosed |
| EP-2181980-A1 | A process for the preparation of (R)-1-aminoindanes | Chemo Ibérica, S.A. (ES) | 2010-05-05 | — | — | EP | disclosed |
| EP-2181980-A1 | A process for the preparation of (R)-1-aminoindanes | Chemo Ibérica, S.A. (ES) | 2010-05-05 | — | — | EP | disclosed |