SCHEMBL341539

SCHEMBL341539

COc1ccc(Nc2ccccc2CC(=O)O)c(C(=O)O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 1/20 0.59
FABP4 P15090 1/20 0.59
MEN1 O00255 2/20 0.55
LMNA P02545 2/20 0.55
KMT2A Q03164 2/20 0.55
HPGD P15428 1/20 0.55
GFER P55789 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
AKR1C3 P42330 7/20 0.55
AKR1C2 P52895 7/20 0.55
POLB P06746 1/20 0.54
MAPT P10636 1/20 0.54
HSD17B10 Q99714 2/20 0.52
AKR1B10 O60218 1/20 0.52
AKR1B1 P15121 1/20 0.52
AKR1C4 P17516 1/20 0.52
AKR1C1 Q04828 1/20 0.52
CXCL8 P10145 3/20 0.51
KDM4E B2RXH2 2/20 0.49
ALDH1A1 P00352 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22720189 0.85 AKR1C3 (0.71) FABP3FABP4MEN1LMNAKMT2A
SCHEMBL9536190 0.84 FABP3 (0.56) FABP3FABP4MEN1LMNAKMT2A
SCHEMBL6141457 0.84 AKR1C3 (0.70) FABP3FABP4MEN1LMNAKMT2A
SCHEMBL22720113 0.83 MEN1 (0.72) FABP3FABP4MEN1LMNAKMT2A
SCHEMBL7164974 0.82 CXCL8 (0.70) FABP3FABP4LMNAKMT2AAKR1C3
SCHEMBL7161900 0.82 AKR1C3 (0.58) MEN1KMT2AHPGDGFERAKR1C3
SCHEMBL10654462 0.81 FABP3 (0.46) FABP3FABP4MEN1LMNAKMT2A
SCHEMBL7166135 0.81 AKR1C3 (0.69) MEN1KMT2AHPGDSMN1; SMN2AKR1C3
SCHEMBL341928 0.80 CXCL8 (0.66) FABP3FABP4MEN1LMNAKMT2A
SCHEMBL9232982 0.80 FABP3 (0.62) FABP3FABP4MEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1975707-B1 Curable composition and planographic printing plate precursor FUJIFILM CORP (JP) 2017-07-19 EP disclosed
EP-1801651-B1 Polymerizable composition and planographic printing plate precursor using the same FUJIFILM CORP (JP) 2017-04-19 EP disclosed
EP-1887423-B1 Laser-decomposable resin composition and pattern-forming material using the same FUJIFILM CORP (JP) 2016-01-27 EP disclosed
EP-1431032-B1 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORP (JP) 2015-12-09 EP disclosed
EP-2039509-B1 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM CORP (JP) 2014-03-26 EP disclosed
US-8110337-B2 Mixture of binder, an unsaturated compound and acid generator; lithography FUJIFILM CORPORATION (JP) 2012-02-07 US disclosed
US-20120015295-A1 INFRARED-SENSITIVE COMPOSITION FOR PRINTING PLATE PRECURSORS CITICORP NORTH AMERICA, INC., AS AGENT 2012-01-19 US disclosed
EP-1862301-B1 Image recording material, planographic printing plate precursor, and planographic printing method using the same FUJIFILM CORP (JP) 2011-09-28 EP disclosed
US-8012671-B2 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-09-06 US disclosed
US-7989140-B2 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-08-02 US disclosed
US-20030003399-A1 Infrared radiation absorbers, radical producers of polyhaloalkyl -substituted compounds, polycarboxylic acids, and leuco dyes; printing plate precursors KODAK AMERICAS LTD. 2003-01-02 US disclosed
US-20020197564-A1 Stabilized infrared-sensitive polymerizable systems KODAK AMERICAS LTD. 2002-12-26 US disclosed
EP-1249343-A2 Thermal initiator system using leuco dyes and polyhalogene compounds Kodak Polychrome Graphics GmbH (DE) 2002-10-16 EP disclosed
US-6309792-B1 MIXTURE OF ABSORBER, FREE RADICAL FORMING COMPOUND AND POLYCARBOXYLIC ACID KODAK POLYCHROME GRAPHICS LLC 2001-10-30 US disclosed
EP-1079972-A1 IR-SENSITIVE COMPOSITION AND USE THEREOF FOR THE PREPARATION OF PRINTING PLATE PRECURSORS Kodak Polychrome Graphics Company Ltd. (US) 2001-03-07 EP disclosed
WO-2000048836-A1 IR-SENSITIVE COMPOSITION AND USE THEREOF FOR THE PREPARATION OF PRINTING PLATE PRECURSORS KODAK POLYCHROME GRAPHICS COMPANY, LTD. (US) 2000-08-24 WO disclosed
EP-0092380-B1 ANTIALLERGIC 4H-FURO(3,2-B)INDOLES AND THEIR PRODUCTION WARNER-LAMBERT COMPANY (US) 1988-01-20 EP disclosed
US-4596814-A Antiallergens WARNER-LAMBERT COMPANY (US) 1986-06-24 US disclosed
US-4503236-A Antiallergic 4Hfuro[3,2-b]indoles WARNER-LAMBERT COMPANY (US) 1985-03-05 US disclosed
EP-0092380-A2 Antiallergic 4H-furo(3,2-b)indoles and their production WARNER-LAMBERT COMPANY (US) 1983-10-26 EP disclosed