SCHEMBL341928

SCHEMBL341928

O=C(O)Cc1ccccc1Nc1ccccc1C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCL8 P10145 4/20 0.66
CLCN2 P51788 1/20 0.59
FABP4 P15090 2/20 0.59
PTGS2 P35354 5/20 0.58
AKR1B10 O60218 2/20 0.58
TRPA1 O75762 2/20 0.58
ABCB11 O95342 2/20 0.58
PTGS1 P23219 2/20 0.58
TTR P02766 2/20 0.58
UGT1A9 O60656 1/20 0.58
MT-CO2 P00403 1/20 0.58
ALB P02768 1/20 0.58
UGT1A6 P19224 1/20 0.58
UGT1A1 P22309 1/20 0.58
CXCR1 P25024 1/20 0.58
ADRA1A P35348 1/20 0.58
AGTR2 P50052 1/20 0.58
NR1I3 Q14994 1/20 0.58
SLC22A6 Q4U2R8 1/20 0.58
NR1H4 Q96RI1 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27516871 0.84 CLCN2 (0.76) CLCN2FABP4PTGS2AKR1B10TRPA1
SCHEMBL30320327 0.83 FABP4 (0.80) CLCN2FABP4PTGS2AKR1B10TRPA1
SCHEMBL355549 0.83 FABP4 (0.80) CLCN2FABP4PTGS2AKR1B10TRPA1
SCHEMBL7165002 0.82 CXCL8 (0.70) CXCL8CLCN2PTGS2AKR1B10TRPA1
SCHEMBL6142375 0.81 FABP4 (0.84) CLCN2FABP4PTGS2AKR1B10TRPA1
SCHEMBL9691899 0.81 FABP4 (0.77) CLCN2FABP4PTGS2AKR1B10TRPA1
SCHEMBL7165423 0.81 CXCL8 (0.68) CXCL8CLCN2PTGS2AKR1B10TRPA1
SCHEMBL341539 0.80 FABP3 (0.59) CXCL8FABP4PTGS2AKR1B10CYP2C9
SCHEMBL29622781 0.80 CXCL8 (0.67) CXCL8CLCN2FABP4PTGS2AKR1B10
SCHEMBL361662 0.80 CXCL8 (0.67) CXCL8CLCN2FABP4PTGS2AKR1B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1975707-B1 Curable composition and planographic printing plate precursor FUJIFILM CORP (JP) 2017-07-19 EP disclosed
EP-1801651-B1 Polymerizable composition and planographic printing plate precursor using the same FUJIFILM CORP (JP) 2017-04-19 EP disclosed
EP-1887423-B1 Laser-decomposable resin composition and pattern-forming material using the same FUJIFILM CORP (JP) 2016-01-27 EP disclosed
EP-1431032-B1 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORP (JP) 2015-12-09 EP disclosed
EP-2039509-B1 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM CORP (JP) 2014-03-26 EP disclosed
US-8110337-B2 Mixture of binder, an unsaturated compound and acid generator; lithography FUJIFILM CORPORATION (JP) 2012-02-07 US disclosed
US-20120015295-A1 INFRARED-SENSITIVE COMPOSITION FOR PRINTING PLATE PRECURSORS CITICORP NORTH AMERICA, INC., AS AGENT 2012-01-19 US disclosed
EP-1862301-B1 Image recording material, planographic printing plate precursor, and planographic printing method using the same FUJIFILM CORP (JP) 2011-09-28 EP disclosed
US-8012671-B2 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-09-06 US disclosed
US-7989140-B2 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-08-02 US disclosed
EP-1079972-A1 IR-SENSITIVE COMPOSITION AND USE THEREOF FOR THE PREPARATION OF PRINTING PLATE PRECURSORS Kodak Polychrome Graphics Company Ltd. (US) 2001-03-07 EP disclosed
WO-2000048836-A1 IR-SENSITIVE COMPOSITION AND USE THEREOF FOR THE PREPARATION OF PRINTING PLATE PRECURSORS KODAK POLYCHROME GRAPHICS COMPANY, LTD. (US) 2000-08-24 WO disclosed
US-5942372-A COMPRISED A SPECTRAL SENSITIZER THAT SENSITIZES IN THE ULTRAVIOLET OR VISIBLE REGIONS OF THE SPECTRUM AND AN N-ARYL POLYCARBOXYLIC ACID CO-INITIATOR; VERY HIGH PHOTOSPEED AND VERY GOOD SHELF-LIFE IN COMPUTER-TO-PLATE SYSTEMS KODAK POLYCHROME GRAPHICS, LLC (US) 1999-08-24 US disclosed
US-5914215-A ELEMENT COMPRISING SUPPORT HAVING PHOTOIMAGEABLE, RADIATION SENSITIVE LAYER COMPRISING UNSATURATED COMPOUND, PHOTOINITIATOR SYSTEM COMPRISING SENSITIZER SENSITIZING IN ULTRAVIOLET OR VISIBLE REGION OF SPECTRUM, CO-INITIATOR KODAK POLYCHROME GRAPHIC, LLC (US) 1999-06-22 US disclosed
US-5888700-A NONFOGGING, SHELF LIFE KODAK POLYCHROME GRPAHICS, LLC (US) 1999-03-30 US disclosed
US-5821030-A DIRECT DIGITAL EXPOSURE; HIGH WRITING SPEED; ADHESION; ANTIFOGGING AGENTS; SHELF LIFE; USING A POLYCARBOXYLIC ACID IN THE PHOTOPOLYMERIZATION INITIATOR SYSTEM AND A BASIC COMPOUND IN THE OXYGEN BARRIER LAYER KODAK POLYCHROME GRAPHICS (US) 1998-10-13 US disclosed
US-5776655-A CONTAINING PHOTOPOLYMER EASTMAN KODAK COMPANY (US) 1998-07-07 US disclosed
EP-0795790-A2 Peel-developable lithographic printing plate EASTMAN KODAK COMPANY (US) 1997-09-17 EP disclosed
US-5629354-A Photopolymerization initiator system comprising a spectral sensitizer and a polycarboxylic acid co-initiator EASTMAN KODAK COMPANY (US) 1997-05-13 US disclosed
EP-0730201-A1 Sensitized photopolymerizable compositions and use thereof in lithographic printing plates EASTMAN KODAK COMPANY (US) 1996-09-04 EP disclosed