Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 5/20 | 0.55 |
| ▸ | CDK1 | P06493 | 5/20 | 0.47 |
| ▸ | IGF1R | P08069 | 3/20 | 0.47 |
| ▸ | MARK3 | P27448 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.47 |
| ▸ | AURKA | O14965 | 2/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.47 |
| ▸ | LYN | P07948 | 2/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.47 |
| ▸ | BLK | P51451 | 2/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.47 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.47 |
| ▸ | MARK2 | Q7KZI7 | 2/20 | 0.47 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | PLK4 | O00444 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5022949 | 0.76 | ADORA3 (0.43) | CDK2MAPTRAB9ACCNE1GAA | |
| SCHEMBL3415683 | 0.75 | CDK2 (0.55) | CDK2CDK1IGF1RMARK3JAK2 | |
| SCHEMBL7500309 | 0.71 | CDK2 (0.51) | CDK2CDK1IGF1RMARK3JAK2 | |
| SCHEMBL6446927 | 0.71 | CDK2 (1.00) | CDK2CDK1IGF1RMARK3JAK2 | |
| SCHEMBL31381352 | 0.70 | MAP3K5 (0.60) | CDK2CDK1IGF1RMARK3JAK2 | |
| SCHEMBL27770482 | 0.70 | MAP3K5 (0.60) | CDK2CDK1IGF1RMARK3JAK2 | |
| SCHEMBL167891 | 0.70 | MAP3K5 (0.60) | CDK2CDK1IGF1RMARK3JAK2 | |
| Benzene SCHEMBL28188863 | 0.70 | MAP3K5 (0.60) | CDK2CDK1IGF1RMARK3JAK2 | |
| SCHEMBL15380926 | 0.70 | CDK2 (0.54) | CDK2CDK1IGF1RMARK3JAK2 | |
| SCHEMBL12120897 | 0.70 | CDK2 (0.54) | CDK2CDK1IGF1RMARK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962634-B2 | 4-amino-3-arylamino-6-arylpyrazolo[3,4-d) pyrimidine derivatives, methods for their preparation and their use as antiviral agents | DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO. KG (DE) | 2015-02-24 | — | — | US | claimed |
| EP-2049540-B1 | 4-AMINO-3-ARYLAMINO-6-ARYLPYRAZOLO[3,4-D]PYRIMIDINE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | DRITTE PATENTPORTFOLIO BETEILI (DE) | 2010-12-22 | — | — | EP | claimed |
| US-20100010018-A1 | 4-Amino-3-Arylamino-6-Arylpyrazolo[3,4-D) Pyrimidine Derivatives, Methods for their Preparation and their Use as Antiviral Agents | DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO. KG (DE) | 2010-01-14 | — | — | US | claimed |
| EP-2049540-A1 | 4-AMINO-3-ARYLAMINO-6-ARYLPYRAZOLO[3,4-D]PYRIMIDINE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | Dritte Patentportfolio Beteiligungsgesellschaft mbH & Co.KG (DE) | 2009-04-22 | — | — | EP | claimed |
| WO-2007147401-A1 | 4-AMINO-3-ARYLAMINO-6-ARYLPYRAZOLO[3,4-D]PYRIMIDINE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO.KG (DE) | 2007-12-27 | — | — | WO | claimed |
| US-8962634-B2 | 4-amino-3-arylamino-6-arylpyrazolo[3,4-d) pyrimidine derivatives, methods for their preparation and their use as antiviral agents | DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO. KG (DE) | 2015-02-24 | — | — | US | disclosed |
| EP-2049540-B1 | 4-AMINO-3-ARYLAMINO-6-ARYLPYRAZOLO[3,4-D]PYRIMIDINE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | DRITTE PATENTPORTFOLIO BETEILI (DE) | 2010-12-22 | — | — | EP | disclosed |
| US-20100010018-A1 | 4-Amino-3-Arylamino-6-Arylpyrazolo[3,4-D) Pyrimidine Derivatives, Methods for their Preparation and their Use as Antiviral Agents | DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO. KG (DE) | 2010-01-14 | — | — | US | disclosed |
| EP-2049540-A1 | 4-AMINO-3-ARYLAMINO-6-ARYLPYRAZOLO[3,4-D]PYRIMIDINE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | Dritte Patentportfolio Beteiligungsgesellschaft mbH & Co.KG (DE) | 2009-04-22 | — | — | EP | disclosed |
| WO-2007147401-A1 | 4-AMINO-3-ARYLAMINO-6-ARYLPYRAZOLO[3,4-D]PYRIMIDINE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO.KG (DE) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100010018-A1 | 4-Amino-3-Arylamino-6-Arylpyrazolo[3,4-D) Pyrimidine Derivatives, Methods for their Preparation and their Use as Antiviral Agents | PNP, TYMP, EIF2AK2 | CDK2 76/4885CDK1 633/4885IGF1R 3664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.