Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 5/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | MDH2 | P40926 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CTSV | O60911 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3409832 | 0.90 | ALDH1A1 (0.68) | FLT3ALDH1A1HPGDKDM4ECYP1A2 | |
| SCHEMBL3030893 | 0.81 | SRD5A2 (0.80) | FLT3ALDH1A1HPGDKDM4ECYP1A2 | |
| SCHEMBL30920873 | 0.81 | SRD5A2 (0.80) | FLT3ALDH1A1HPGDKDM4ECYP1A2 | |
| SCHEMBL6087004 | 0.79 | FLT3 (0.66) | FLT3ALDH1A1HPGDKDM4ECYP1A2 | |
| SCHEMBL9949523 | 0.79 | FLT3 (0.57) | FLT3ALDH1A1HPGDKDM4ECYP1A2 | |
| SCHEMBL27635516 | 0.78 | SRD5A2 (0.62) | FLT3ALDH1A1HPGDKDM4ECYP1A2 | |
| SCHEMBL3420585 | 0.77 | FLT3 (0.54) | FLT3ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL8406972 | 0.77 | FLT3 (0.70) | FLT3ALDH1A1HPGDKDM4ECYP1A2 | |
| SCHEMBL8111841 | 0.77 | KDM4E (0.52) | FLT3ALDH1A1HPGDKDM4ECYP1A2 | |
| SCHEMBL18886838 | 0.77 | ALDH1A1 (0.61) | FLT3ALDH1A1HPGDKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2149552-A1 | 5,6 substituted benzamide derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | claimed |