Adenine

Adenine

SCHEMBL3416954

Nc1ncnc2[nH]cnc12.Nc1ncnc2[nH]cnc12

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 7/20 0.48
PI4K2B Q8TCG2 7/20 0.48
PI4K2A Q9BTU6 7/20 0.48
PI4KB Q9UBF8 7/20 0.48
XDH P47989 2/20 0.48
LRRK2 Q5S007 2/20 0.48
LMNA P02545 1/20 0.48
DRD3 P35462 1/20 0.48
ADORA2A P29274 4/20 0.41
ADORA1 P30542 4/20 0.41
RET P07949 1/20 0.39
ERAP1 Q9NZ08 1/20 0.39
GDA Q9Y2T3 2/20 0.34
PNP P00491 1/20 0.34
ADORA2B P29275 2/20 0.33
PDPK1 O15530 1/20 0.33
BTK Q06187 1/20 0.33
PRKCI P41743 1/20 0.33
PARP1 P09874 1/20 0.33
MAP4K4 O95819 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenine SCHEMBL3413247 1.00 PI4KA (0.48) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL8110 1.00 PI4KA (0.48) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL3414603 1.00 PI4KA (0.48) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL11798390 0.98 PI4KA (0.50) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL5601016 0.98 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL691914 0.98 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL7204509 0.98 PI4KA (0.50) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL9214447 0.98 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL2895675 0.98 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL10868999 0.98 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109390037-A The full site recognition methods of mature miRNA based on SVM-AdaBoost 齐齐哈尔大学 2019-02-26 CN claimed
CN-100420443-C Nucleotide analog composition and synthesis method GILEAD SCIENCES INC (US) 2008-09-24 CN claimed
WO-2021076887-A1 CAL-T CONSTRUCTS AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2021-04-22 WO disclosed
EP-3512486-A1 BLUE POWDER AND USE THEREOF IN COSMETICS L'Oreal (FR) 2019-07-24 EP disclosed
US-20190214145-A1 Method and systems for creating and screening patient metabolite profile to diagnose current medical condition, diagnose current treatment state and recommend new treatment regimen KUREK ITZHAK (US) 2019-07-11 US disclosed
CN-109390037-A The full site recognition methods of mature miRNA based on SVM-AdaBoost 齐齐哈尔大学 2019-02-26 CN disclosed
WO-2018160158-A1 SYNERGISTIC COMPOSITION FOR MAINTENANCE OF HEALTHY BALANCE OF MICROFLORA KIMBERLY-CLARK WORLDWIDE, INC. (US) 2018-09-07 WO disclosed
EP-3344751-A1 METHODS AND COMPOSITIONS FOR MODULATING PRFA MEDIATED VIRULENCE GENE ACTIVATION INLISTERIA SPP The Regents of the University of California (US) 2018-07-11 EP disclosed
WO-2018050504-A1 BLUE POWDER AND USE THEREOF IN COSMETICS L'OREAL (FR) 2018-03-22 WO disclosed
WO-2017040859-A1 METHODS AND COMPOSITIONS FOR MODULATING PRFA MEDIATED VIRULENCE GENE ACTIVATION IN LISTERIA SPP. THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-03-09 WO disclosed
CN-103937693-B Wine brewing yeast strain and application thereof 浙江大学 2016-11-23 CN disclosed
US-6866999-B2 Diagnostic methods based upon a particular genotype in the Tumor Necrosis Factor (TNF alpha ) gene MIDDLESEX SAVINGS BANK 2005-03-15 US disclosed
US-20020086016-A1 Diagnostic methods based upon a particular genotype in the Tumor Necrosis Factor (TNF alpha ) gene MIDDLESEX SAVINGS BANK 2002-07-04 US disclosed
WO-2002031194-A1 METHOD OF DIAGNOSING AND TREATING INCREASED RISK OF DEATH FROM COMMUNITY-ACQUIRED PNEUMONIA ASSOCIATED WITH THE A ALLELE OF THE TNFα-238 POLYMORPHISM GENOMICS COLLABORATIVE, INC. (US) 2002-04-18 WO disclosed
WO-2002031197-A1 METHOD FOR IDENTIFYING INCREASED RISK OF DEATH FROM COMMUNITY ACQUIRED PNEUMONIA WUNDERINK RICHARD G (US) 2002-04-18 WO disclosed
US-6294339-B1 MONITORING GENOME FOR DETECTION OF PREFERENTIAL GENOTYPES ASSOCIATED WITH DEATH; DETERMINE THE GENOTYPE OF TUMOR NECROSIS FACTOR ALLELES IN HUMANS AND EVALUATE POSSIBILITY OF DEATH OF HUMANS WITH ALLELES SERACARE LIFE SCIENCES, INC. 2001-09-25 US disclosed
WO-2000014268-A9 MODULATION OF MICROBIAL METABOLISM AND/OR GROWTH RATE BY PLANT GROWTH HORMONES EDBERG STEPHEN C (US) 2000-08-17 WO disclosed
EP-1005478-A1 RIBONUCLEOSIDE-DERIVATIVE AND METHOD FOR PREPARING THE SAME Pitsch, Stefan (CH) 2000-06-07 EP disclosed
WO-1999009044-A1 RIBONUCLEOSIDE-DERIVATIVE AND METHOD FOR PREPARING THE SAME PITSCH STEFAN (CH) 1999-02-25 WO disclosed
US-5217858-A Radiation sensitive silver halide emulsion containing at least fifty mole percent silver chloride grains which have crystal face stabilizer adsorbed onto the faces thereof EASTMAN KODAK COMPANY (US) 1993-06-08 US disclosed