Adenine

Adenine

SCHEMBL8110

Nc1ncnc2[nH]cnc12

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 7/20 0.48
PI4K2B Q8TCG2 7/20 0.48
PI4K2A Q9BTU6 7/20 0.48
PI4KB Q9UBF8 7/20 0.48
XDH P47989 2/20 0.48
LRRK2 Q5S007 2/20 0.48
LMNA P02545 1/20 0.48
DRD3 P35462 1/20 0.48
ADORA2A P29274 4/20 0.41
ADORA1 P30542 4/20 0.41
RET P07949 1/20 0.39
ERAP1 Q9NZ08 1/20 0.39
GDA Q9Y2T3 2/20 0.34
PNP P00491 1/20 0.34
ADORA2B P29275 2/20 0.33
PDPK1 O15530 1/20 0.33
BTK Q06187 1/20 0.33
PRKCI P41743 1/20 0.33
PARP1 P09874 1/20 0.33
MAP4K4 O95819 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenine SCHEMBL3413247 1.00 PI4KA (0.48) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL3416954 1.00 PI4KA (0.48) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL3414603 1.00 PI4KA (0.48) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL11798390 0.98 PI4KA (0.50) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL5601016 0.98 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL691914 0.98 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL7204509 0.98 PI4KA (0.50) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL9214447 0.98 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL2895675 0.98 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL10868999 0.98 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 294838 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US claimed
EP-4748395-A1 THERAPY BASED ON INTRACEREBRAL PHOSPHATE HOMEOSTASIS PROMOTER Shanghai Anyea Therapeutics Co., Ltd (CN) 2026-05-27 EP claimed
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
EP-4747387-A1 COAGULATION FACTOR XI-MODULATING COMPOSITIONS AND METHODS OF USE THEREOF Adarx Pharmaceuticals, Inc. (US) 2026-05-27 EP claimed
EP-4223352-B1 DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS UROTRONIC INC (US) 2026-05-27 EP claimed
EP-4746696-A1 METHOD OF DETECTING MAIZE PLANTS WITH ALTERED ALEURONE ANTHOCYANIN CONTENT AND ASSOCIATED MARKER ALLELES AND HAPLOTYPES Agreliant Genetics, LLC (US) 2026-05-27 EP claimed
EP-4747003-A1 <SUP2/>? <SUB2/>?2?A STEAM-STABLE THREE-DIMENSIONAL (3D) ZINC-ADENINATE METAL ORGANIC FRAMEWORK WITH A HIGH SELECTIVITY FOR INDUSTRIAL COCAPTURE Svante Technologies Inc. (CA) 2026-05-27 EP claimed
CN-122095090-A Compounds and methods for reducing ATN1 expression 2026-05-26 CN claimed
US-12636301-B2 5′-modified carbocyclic ribonucleotide derivatives and methods of use SANEGENE BIO USA INC. (US) 2026-05-26 US claimed
CN-122080221-A CoolMPS antibody mutant capable of specifically binding cytosine deoxynucleotide with blocking modification and application thereof 2026-05-26 CN claimed
US-4035239-A REACTION WITH ADENOSINE TRIPHOSPHATE, PHOSPHOTRANSACETYLASE ENZYME MCCLOSKEY LEO P 1977-07-12 US claimed
US-4028184-A CULTURING CORYNEBACTERIUM, ARTHROBACTER, MICROBACTERIUM KIKKOMAN SHOYU CO., LTD. (JA) 1977-06-07 US claimed
US-4022667-A Substrate solution for carboxylic ester hydrolase determination THE UNIVERSITY OF ALABAMA (US) 1977-05-10 US claimed
US-3989833-A Pharmaceutical compositions containing adenine derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-11-02 US claimed
US-3982948-A Process for preparing silver halide emulsion containing a rhodium salt and a decomposition product of nucleic acid KONISHIROKU PHOTO CO. LTD. (JA) 1976-09-28 US claimed
US-3969188-A Method of producing guanosine by fermentation AJINOMOTO CO., INC. (JA) 1976-07-13 US claimed
US-3960661-A MUTANT BACILLUS SUBTILIS REQUIRING ADENINE FOR GROWTH AJINOMOTO CO., INC. (JA) 1976-06-01 US claimed
US-3960660-A BACILLUS MUTANT REQUIRING ADENINE FOR GROWTH AJINOMOTO CO., INC. (JA) 1976-06-01 US claimed
US-3939089-A PEROXYSULFATE TOKAI DENKA KOGYO KABUSHIKI KAISHA (JA) 1976-02-17 US claimed
US-3937809-A ADDITION COMPOUND OF A NUCLEOTIDE AND AN AMINO ACID AND THE USE THEREOF IN PROTECTION AGAINST ACTINIC RADIATION KOLMAR LABORATORIES, INC. (US) 1976-02-10 US claimed