Adenine

Adenine

SCHEMBL9214447

Nc1ncnc2[nH]cnc12.[NaH]

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 7/20 0.47
PI4K2B Q8TCG2 7/20 0.47
PI4K2A Q9BTU6 7/20 0.47
PI4KB Q9UBF8 7/20 0.47
XDH P47989 2/20 0.47
LRRK2 Q5S007 2/20 0.47
LMNA P02545 1/20 0.47
DRD3 P35462 1/20 0.47
ADORA2A P29274 4/20 0.39
ADORA1 P30542 4/20 0.39
RET P07949 1/20 0.38
ERAP1 Q9NZ08 1/20 0.38
GDA Q9Y2T3 2/20 0.33
PNP P00491 1/20 0.33
BTK Q06187 1/20 0.33
ADORA2B P29275 2/20 0.32
PARP1 P09874 1/20 0.32
PDPK1 O15530 1/20 0.32
PRKCI P41743 1/20 0.32
MAP4K4 O95819 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenine SCHEMBL27739991 1.00 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL4887728 0.98 PI4KA (0.45) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL3416954 0.98 PI4KA (0.48) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL3413247 0.98 PI4KA (0.48) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL8110 0.98 PI4KA (0.48) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL3414603 0.98 PI4KA (0.48) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL2895675 0.95 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL7204509 0.95 PI4KA (0.50) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL20485928 0.95 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBXDH
Adenine SCHEMBL10868999 0.95 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106342838-B A kind of plant growth regualting composition, preparation and its application 四川国光农化股份有限公司 2018-11-27 CN claimed
CN-106342838-A Compound for regulating plant growth, and preparation and application thereof 四川国光农化股份有限公司 2017-01-25 CN claimed
EP-4225329-A2 METHOD AND DEVICE FOR PREPARING UNIVERSAL PLASMA Universitätsmedizin Greifswald (DE) 2023-08-16 EP disclosed
WO-2022073966-A2 METHOD AND DEVICE FOR PREPARING UNIVERSAL PLASMA Universität Greifswald (DE) 2022-04-14 WO disclosed
CN-113151378-A Method for preparing nucleoside, nicotinic acid adenine dinucleotide and nicotinic acid mononucleotide of nicotinic acid or derivative thereof, enzyme composition and application 百瑞全球有限公司 2021-07-23 CN disclosed
CN-111269876-A Method for in vitro fertilization and embryo culture by in vivo collection of bovine oocytes 天津博裕力牧科技有限公司 2020-06-12 CN disclosed
CN-110664655-A Cell culture solution 西安博和医疗科技有限公司 2020-01-10 CN disclosed
CN-106342838-B A kind of plant growth regualting composition, preparation and its application 四川国光农化股份有限公司 2018-11-27 CN disclosed
CN-107260563-A Contain lauroyl alanine sodium salt as the toothpaste of surfactant 苏州三君日化科技有限公司 2017-10-20 CN disclosed
CN-106342838-A Compound for regulating plant growth, and preparation and application thereof 四川国光农化股份有限公司 2017-01-25 CN disclosed
CN-102939291-B Phosphonate ester for the toxicity with reduction for the treatment of of viral infections 加利福尼亚大学董事会 2016-09-07 CN disclosed
EP-0347852-A2 Novel neplanocin derivatives MERRELL DOW PHARMACEUTICALS INC. (US) 1989-12-27 EP disclosed
US-4859677-A Nucleoside analogues having antiviral activity UNIVERSITY OF KANSAS (US) 1989-08-22 US disclosed
US-4622324-A CARDIOVASCULAR DISORDERS, HYPOTENSIVES DR. WILLMAR SCHWABE GMBH & CO. (DE) 1986-11-11 US disclosed
US-4617304-A VIRICIDE; HERPES MERCK & CO., INC. (US) 1986-10-14 US disclosed
EP-0159264-A2 Antiviral compounds MERCK & CO. INC. (US) 1985-10-23 EP disclosed
US-4542137-A NONEXPLOSIVE, CARDIOVASCULAR DR. WILLMAR SCHWABE GMBH & CO. (DE) 1985-09-17 US disclosed
US-4535158-A CHEMICXAL INTERMEDIATES FOR CARDIOTONIC AGENTS DR. WILLMAR SCHWABE GMBH & CO. 1985-08-13 US disclosed
US-4479951-A CORONARY DIESASE DR. WILLMAR SCHWABE GMBH & CO. (DE) 1984-10-30 US disclosed
US-4413122-A Optionally N-substituted aminodesoxy-1.4;3.6-dianhydrohexitol derivatives FA. WILMAR SCHWABE GMBH & CO. (DE) 1983-11-01 US disclosed