SCHEMBL3417166

SCHEMBL3417166

CCc1ccccc1C1(CC)OC1(CC)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.40
HDAC4 P56524 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
PDK2 Q15119 2/20 0.33
TSHR P16473 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
CYP1A2 P05177 1/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
CYP2C19 P33261 3/20 0.33
CYP2C9 P11712 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
HCAR3 P49019 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
CFTR P13569 1/20 0.33
GOPC Q9HD26 1/20 0.33
GABRA1 P14867 2/20 0.31
GABRB2 P47870 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10889346 0.71 TSHR (0.36) SMN1; SMN2MEN1KMT2ATSHRTDP1
SCHEMBL19809196 0.70 TSHR (0.35) SMN1; SMN2MEN1KMT2ATSHRTDP1
SCHEMBL9817499 0.67 HCAR3 (0.40) MEN1KMT2ATSHRTDP1CYP1A2
SCHEMBL3622122 0.66 HDAC4 (0.50) CYP2D6HDAC4
Benzene SCHEMBL11603070 0.65 TP53 (0.56) CYP2D6NPSR1GABRA1GABRB2L3MBTL1
Benzene SCHEMBL3122858 0.65 TP53 (0.56) CYP2D6NPSR1GABRA1GABRB2L3MBTL1
Benzene SCHEMBL25402370 0.62 TP53 (0.53) CYP2D6NPSR1GABRA1GABRB2L3MBTL1
Hydrogen Peroxide SCHEMBL11205186 0.62 GABRA1 (0.60) TSHRNPSR1GABRA1GABRB2L3MBTL1
Hydrogen Peroxide SCHEMBL10890655 0.62 GABRA1 (0.60) TSHRNPSR1GABRA1GABRB2L3MBTL1
SCHEMBL36294 0.62 GABRA1 (0.58) CYP2D6NPSR1GABRA1GABRB2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9216547-B2 Method and apparatus for making an object ZYDEX PTY LTD (AU) 2015-12-22 US disclosed
EP-2790897-A1 METHOD AND APPARATUS FOR MAKING AN OBJECT Zydex Pty Ltd (AU) 2014-10-22 EP disclosed
WO-2013091003-A1 METHOD AND APPARATUS FOR MAKING AN OBJECT ZYDEX PTY LTD (AU) 2013-06-27 WO disclosed
US-8398224-B2 Heat activated printing process SAWGRASS TECHNOLOGIES, INC. (US) 2013-03-19 US disclosed
US-8337006-B2 Energy activated printing process SAWGRASS TECHNOLOGIES, INC. (US) 2012-12-25 US disclosed
EP-1853431-B1 Methods of digital printing with reactive inks SAWGRASS TECHNOLOGIES INC D B A SAWGRASS INC (US) 2012-08-29 EP disclosed
US-20100091058-A1 HEAT ACTIVATED PRINTING PROCESS SAWGRASS TECHNOLOGIES, INC. 2010-04-15 US disclosed
US-20100073408-A1 ENERGY ACTIVATED PRINTING PROCESS SAWGRASS TECHNOLOGIES, INC. 2010-03-25 US disclosed
US-7654660-B2 Energy activated printing process SAWGRASS TECHNOLOGIES, INC. (US) 2010-02-02 US disclosed
US-20090021568-A1 Reactive Dye and Process of Printing Same XU MING 2009-01-22 US disclosed
US-6341856-B1 Ink jet printing process using reactive inks SAWGRASS SYSTEMS, INC. 2002-01-29 US disclosed
WO-2001098091-A2 INTERMEDIATE TRANSFER RECORDING MEDIUM SAWGRASS SYSTEMS, INC. (US) 2001-12-27 WO disclosed
EP-1133395-A1 REACTIVE INK PRINTING PROCESS SAWGRASS SYSTEMS, INC. (US) 2001-09-19 EP disclosed
EP-1102676-A1 REACTIVE INK PRINTING PROCESS SAWGRASS SYSTEMS, INC. (US) 2001-05-30 EP disclosed
EP-1089879-A1 INK JET PRINTING PROCESS USING REACTIVE INKS SAWGRASS SYSTEMS, INC. (US) 2001-04-11 EP disclosed
WO-2000064681-A1 INK JET PRINTING PROCESS USING REACTIVE INKS SAWGRASS SYSTEMS, INC. (US) 2000-11-02 WO disclosed
US-6105502-A Reactive ink printing process SAWGRASS SYSTEMS, INC. (US) 2000-08-22 US disclosed
US-6103041-A DIGITAL PRINTING USING WAX RIBBON HAVING LAYER OF INK CONTAINING HEAT-MELTABLE COMPOUNDS WHICH REACT WITH ACTIVE HYDROGENS AND ALSO ACTIVE HYDROGEN COMPOUNDS, FOR FORMING BINDERS WHEN HEAT ACTIVATED TO FORM DURABLE IMAGES SAWGRASS TECHNOLOGIES, INC. 2000-08-15 US disclosed
WO-2000020218-A1 REACTIVE INK PRINTING PROCESS SAWGRASS SYSTEMS, INC. (US) 2000-04-13 WO disclosed
WO-1999056948-A1 REACTIVE INK PRINTING PROCESS SAWGRASS SYSTEMS, INC. (US) 1999-11-11 WO disclosed