D-Glutamate

D-Glutamate

SCHEMBL3417211

NC(CCC(=O)O)C(=O)O.c1ccc2cccc-2cc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 2/20 0.67
SLC1A2 P43004 2/20 0.67
SLC1A1 P43005 2/20 0.67
GRM8 O00222 1/20 0.67
GRM6 O15303 1/20 0.67
GRIN2D O15399 1/20 0.67
GRIN3B O60391 1/20 0.67
GSR P00390 1/20 0.67
CYP1A2 P05177 1/20 0.67
GRIK1 P39086 1/20 0.67
GRM5 P41594 1/20 0.67
GRIA1 P42261 1/20 0.67
GRIA2 P42262 1/20 0.67
GRIA3 P42263 1/20 0.67
GRIA4 P48058 1/20 0.67
GRIN1 Q05586 1/20 0.67
GRIN2A Q12879 1/20 0.67
GRIK2 Q13002 1/20 0.67
GRIK3 Q13003 1/20 0.67
GRIN2B Q13224 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamic Acid SCHEMBL3417216 1.00 SLC1A3 (0.67) SLC1A3SLC1A2SLC1A1GRM8GRM6
Biphenyl SCHEMBL7780462 0.98 SLC1A3 (0.69) SLC1A3SLC1A2SLC1A1GRM8GRM6
D-Glutamate SCHEMBL10752501 0.89 GRIA2 (0.62) SLC1A3SLC1A2SLC1A1GRM8GRM6
D-Glutamate SCHEMBL6486892 0.86 GRM8 (0.90) SLC1A3SLC1A2SLC1A1GRM8GRM6
D-Glutamate SCHEMBL28184847 0.86 SLC1A3 (0.62) SLC1A3SLC1A2SLC1A1GRM8GRM6
Biphenyl SCHEMBL8982408 0.85 KMT2A (0.70) SLC1A3SLC1A2SLC1A1GRM8GRM6
Biphenyl SCHEMBL8982412 0.85 KMT2A (0.70) SLC1A3SLC1A2SLC1A1GRM8GRM6
Glutamic Acid SCHEMBL7715353 0.85 GRM8 (0.67) SLC1A3SLC1A2SLC1A1GRM8GRM6
D-Glutamate SCHEMBL7715349 0.85 GRM8 (0.67) SLC1A3SLC1A2SLC1A1GRM8GRM6
Glutamic Acid SCHEMBL8648352 0.84 GRIK1 (0.64) SLC1A3SLC1A2SLC1A1GRM8GRM6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8263123-B2 Rapidly disintegrating tablet containing polyvinyl alcohol EISAI R&D MANAGEMENT CO., LTD. (JP) 2012-09-11 US disclosed
US-7727548-B2 Rapidly disintegrable tablet containing polyvinyl alcohol EISAI R&D MANAGEMENT CO., LTD. (JP) 2010-06-01 US disclosed
US-20080014262-A1 Rapidly disintegrating tablet containing polyvinyl alcohol MORITA YUTAKA 2008-01-17 US disclosed
US-20030086967-A1 Rapidly disintegrable tablet containing polyvinyl alcohol EISAI R&D MANAGEMENT CO., LTD. (JP) 2003-05-08 US disclosed
EP-1260215-A1 RAPIDLY DISINTEGRABLE TABLET CONTAINING POLYVINYL ALCOHOL Eisai Co., Ltd. (JP) 2002-11-27 EP disclosed