Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 2/20 | 0.67 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.67 |
| ▸ | GRM6 | O15303 | 1/20 | 0.67 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.67 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.67 |
| ▸ | GSR | P00390 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.67 |
| ▸ | GRM5 | P41594 | 1/20 | 0.67 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.67 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.67 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.67 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.67 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.67 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.67 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.67 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.67 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.67 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.67 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Glutamate SCHEMBL7715349 | 1.00 | GRM8 (0.67) | GRM8GRM4GRM6GRIN2DGRIN3B | |
| Glutamine SCHEMBL15269081 | 0.87 | KMT2A (0.68) | GRM8GRM4GRM6GRIN2DGRIN3B | |
| Glutamine SCHEMBL15269077 | 0.87 | KMT2A (0.68) | GRM8GRM4GRM6GRIN2DGRIN3B | |
| Biphenyl SCHEMBL7780462 | 0.87 | SLC1A3 (0.69) | GRM8GRM4GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL6486892 | 0.86 | GRM8 (0.90) | GRM8GRM4GRM6GRIN2DGRIN3B | |
| Tyrosine SCHEMBL22500854 | 0.86 | SLC7A5 (0.71) | GRM8GRM4GRM6GRIN2DGRIN3B | |
| Glutamic Acid SCHEMBL11625149 | 0.86 | GRM8 (0.62) | GRM8GRM4GRM6GRIN2DGRIN3B | |
| Glutamic Acid SCHEMBL3417216 | 0.85 | SLC1A3 (0.67) | GRM8GRM4GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL3417211 | 0.85 | SLC1A3 (0.67) | GRM8GRM4GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL7782949 | 0.84 | GRIK1 (0.64) | GRM8GRM4GRM6GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105777790-B | A kind of adjacent carborane phenol derivatives and its preparation method and application | 南京远淑医药科技有限公司 | 2017-11-14 | — | — | CN | disclosed |
| CN-103039645-A | Lotus Fuzhuan brick tea and preparation method thereof | HE ZHIHONG | 2013-04-17 | — | — | CN | disclosed |
| US-6436691-B1 | CONJUGATE WHICH IS SUBSTANTIALLY NON-IMMUNOGENIC IN HUMANS COMPRISING TARGETING MOIETY CAPABLE OF BINDING WITH TUMOR ASSOCIATED ANTIGEN LINKED TO MUTATED FORM OF CARBOXYPEPTIDASE B ENZYME CAPABLE OF CONVERTING PRODRUG INTO ANTICANCER DRUG | ZENECA LIMITED (GB) | 2002-08-20 | — | — | US | disclosed |
| EP-0806964-B1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2002-08-14 | — | — | EP | disclosed |
| EP-0780167-B1 | A method and apparatus for diffusing a chemical solution, a method and apparatus for injecting a liquid, and a method of remedying soil | CANON KK (JP) | 2000-06-07 | — | — | EP | disclosed |
| US-5985281-A | ANTIBODY DIRECTED ENZYME PRODRUG THERAPY (ADEPT) USING A NON-NATURALLY OCCURING MUTANT FORM OF A HOST ENZYME, ESPECIALLY A MUTANT FORM OF RIBONUCLEASE. | ZENECA LIMITED (GB) | 1999-11-16 | — | — | US | disclosed |
| US-5877390-A | USING GAS PRESSURE | CANON KABUSHIKI KAISHA (JP) | 1999-03-02 | — | — | US | disclosed |
| EP-0844885-A2 | CHEMICAL COMPOUNDS | ZENECA LIMITED (GB) | 1998-06-03 | — | — | EP | disclosed |
| EP-0806964-A1 | CHEMICAL COMPOUNDS | ZENECA LIMITED (GB) | 1997-11-19 | — | — | EP | disclosed |
| EP-0780167-A1 | A method and apparatus for diffusing a chemical solution, a method and apparatus for injecting a liquid, and a method of remedying soil | CANON KABUSHIKI KAISHA (JP) | 1997-06-25 | — | — | EP | disclosed |
| WO-1997007769-A2 | CHEMICAL COMPOUNDS | ZENECA LIMITED (GB) | 1997-03-06 | — | — | WO | disclosed |
| WO-1996020011-A1 | CHEMICAL COMPOUNDS | ZENECA LIMITED (GB) | 1996-07-04 | — | — | WO | disclosed |