Biphenyl

Biphenyl

SCHEMBL7780462

NC(CCC(=O)O)C(=O)O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 2/20 0.69
SLC1A2 P43004 2/20 0.69
SLC1A1 P43005 2/20 0.69
GRM8 O00222 1/20 0.69
GRM6 O15303 1/20 0.69
GRIN2D O15399 1/20 0.69
GRIN3B O60391 1/20 0.69
GSR P00390 1/20 0.69
CYP1A2 P05177 1/20 0.69
GRIK1 P39086 1/20 0.69
GRM5 P41594 1/20 0.69
GRIA1 P42261 1/20 0.69
GRIA2 P42262 1/20 0.69
GRIA3 P42263 1/20 0.69
GRIA4 P48058 1/20 0.69
GRIN1 Q05586 1/20 0.69
GRIN2A Q12879 1/20 0.69
GRIK2 Q13002 1/20 0.69
GRIK3 Q13003 1/20 0.69
GRIN2B Q13224 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
D-Glutamate SCHEMBL3417211 0.98 SLC1A3 (0.67) SLC1A3SLC1A2SLC1A1GRM8GRM6
Glutamic Acid SCHEMBL3417216 0.98 SLC1A3 (0.67) SLC1A3SLC1A2SLC1A1GRM8GRM6
D-Glutamate SCHEMBL6486892 0.88 GRM8 (0.90) SLC1A3SLC1A2SLC1A1GRM8GRM6
D-Glutamate SCHEMBL10752501 0.87 GRIA2 (0.62) SLC1A3SLC1A2SLC1A1GRM8GRM6
Biphenyl SCHEMBL8982408 0.87 KMT2A (0.70) SLC1A3SLC1A2SLC1A1GRM8GRM6
Biphenyl SCHEMBL8982412 0.87 KMT2A (0.70) SLC1A3SLC1A2SLC1A1GRM8GRM6
Glutamic Acid SCHEMBL7715353 0.87 GRM8 (0.67) SLC1A3SLC1A2SLC1A1GRM8GRM6
D-Glutamate SCHEMBL7715349 0.87 GRM8 (0.67) SLC1A3SLC1A2SLC1A1GRM8GRM6
Glutamic Acid SCHEMBL8648352 0.85 GRIK1 (0.64) SLC1A3SLC1A2SLC1A1GRM8GRM6
Phthalic Acid SCHEMBL8407913 0.85 CYP1A2 (0.64) SLC1A3SLC1A2SLC1A1GRM8GRM6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1135398-A1 CYANOPHOSPHONAMIDES AND METHOD FOR PREPARATION Monsanto Technology LLC (US) 2001-09-26 EP disclosed
US-6218563-B1 Cyanophosphonamides and method for preparation MONSANTO COMPANY 2001-04-17 US disclosed
WO-2000032611-A1 CYANOPHOSPHONAMIDES AND METHOD FOR PREPARATION MONSANTO TECHNOLOGY LLC (US) 2000-06-08 WO disclosed