Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 11/20 | 0.56 |
| ▸ | ACHE | P22303 | 10/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL684282 | 0.84 | MAOB (0.62) | BCHEMAOBALOX5KMT2ASMN1; SMN2 | |
| SCHEMBL1566108 | 0.82 | KMT2A (0.60) | BCHEMAOBALOX5KMT2ASMN1; SMN2 | |
| SCHEMBL2749197 | 0.81 | KMT2A (0.63) | BCHEMAOBALOX5KMT2ASMN1; SMN2 | |
| SCHEMBL28969190 | 0.81 | MAOB (0.58) | BCHEMAOBALOX5KMT2ASMN1; SMN2 | |
| SCHEMBL12221485 | 0.81 | KMT2A (0.61) | BCHEMAOBALOX5KMT2ASMN1; SMN2 | |
| SCHEMBL23923495 | 0.81 | KMT2A (0.61) | BCHEMAOBALOX5KMT2ASMN1; SMN2 | |
| SCHEMBL27733470 | 0.81 | MAOB (0.58) | BCHEMAOBALOX5KMT2ASMN1; SMN2 | |
| SCHEMBL31748975 | 0.81 | KMT2A (0.61) | BCHEMAOBALOX5KMT2ASMN1; SMN2 | |
| SCHEMBL29216490 | 0.81 | KMT2A (0.58) | BCHEMAOBALOX5KMT2ASMN1; SMN2 | |
| SCHEMBL5772666 | 0.81 | SMN1; SMN2 (0.67) | BCHEMAOBALOX5KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101823970-B | Synthetic method of rivastigmine and intermediates thereof | JIANGSU NHWA PHARMACEUTICAL CO LTD | 2013-05-08 | — | — | CN | claimed |
| CN-101823970-A | Synthetic method of rivastigmine and intermediates thereof | JIANGSU NHWA PHARMACEUTICAL CO LTD | 2010-09-08 | — | — | CN | claimed |
| CN-101823970-B | Synthetic method of rivastigmine and intermediates thereof | JIANGSU NHWA PHARMACEUTICAL CO LTD | 2013-05-08 | — | — | CN | disclosed |
| WO-2010099745-A1 | PREPARATION METHODS OF RIVASTIGMINE AND ITS INTERMEDIATE | 江苏恩华药业股份有限公司 (CN) | 2010-09-10 | — | — | WO | disclosed |
| CN-101823970-A | Synthetic method of rivastigmine and intermediates thereof | JIANGSU NHWA PHARMACEUTICAL CO LTD | 2010-09-08 | — | — | CN | disclosed |