Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.62 |
| ▸ | BCHE | P06276 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.56 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL27575662 | 0.95 | KMT2A (0.58) | MAOBBCHEKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL26378372 | 0.94 | MAOB (0.59) | MAOBBCHEKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL12961031 | 0.90 | MRGPRX4 (0.58) | MAOBBCHEKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL28969190 | 0.87 | MAOB (0.58) | MAOBBCHEKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL31748975 | 0.87 | KMT2A (0.61) | MAOBBCHEKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL23923495 | 0.87 | KMT2A (0.61) | MAOBBCHEKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9946031 | 0.87 | MAOB (0.64) | MAOBBCHEKMT2ASMN1; SMN2MAOA | |
| SCHEMBL2749197 | 0.87 | KMT2A (0.63) | MAOBBCHEKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL12221485 | 0.87 | KMT2A (0.61) | MAOBBCHEKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL27733470 | 0.87 | MAOB (0.58) | MAOBBCHEKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912693-B2 | Compounds for modulating S1P1 activity and methods of using the same | TREVENA, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-20230234946-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | TREVENA, INC. | 2023-07-27 | — | — | US | disclosed |
| US-20230167081-A1 | 5-AMINO-2-PIPERIDINON-3-YL-1-OXOISOINDOLINE DERIVATIVES FOR DEGRADATION OF IKZF2 DEGRADERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-06-01 | — | — | US | disclosed |
| EP-4110760-A1 | GPR40 AGONISTS | Kallyope, Inc. (US) | 2023-01-04 | — | — | EP | disclosed |
| WO-2022234965-A1 | HETEROARYL DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | 주식회사 보로노이 | 2022-11-10 | — | — | WO | disclosed |
| US-20220017762-A1 | INK JET INK FOR FORMING AN INFRARED ABSORBING IMAGE, INFRARED ABSORBING IMAGE FORMING METHOD, AND RECORDED MATERIAL | FUJIFILM CORPORATION (JP) | 2022-01-20 | — | — | US | disclosed |
| WO-2021222542-A1 | 5-AMINO-2-PIPERIDINON-3-YL-1-OXOISOINDOLINE DERIVATIVES FOR DEGRADATION OF IKZF2 DEGRADERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-11-04 | — | — | WO | disclosed |
| WO-2020253870-A1 | 6-HYDRAZINOADENOSINE COMPOUND HAVING A2A ADENOSINE RECEPTOR AGONIST ACTIVITY | 中国人民解放军军事科学院军事医学研究院 | 2020-12-24 | — | — | WO | disclosed |
| US-20200369901-A1 | DISPERSION, INK JET RECORDING METHOD, RECORDED MATERIAL, AND COMPOUND | FUJIFILM CORPORATION (JP) | 2020-11-26 | — | — | US | disclosed |
| US-20200347252-A1 | INK COMPOSITION FOR INK JET PRINTING, IMAGE FORMING METHOD, AND RECORDED MATERIAL | FUJIFILM CORPORATION (JP) | 2020-11-05 | — | — | US | disclosed |
| US-20070078184-A1 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
| EP-1679304-A1 | AMINO ALCOHOL DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USE OF THESE | Kissei Pharmaceutical Co., Ltd. (JP) | 2006-07-12 | — | — | EP | disclosed |
| CN-1523015-A | 2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines | �Ʒ� | 2004-08-25 | — | — | CN | disclosed |
| CN-1515554-A | Intermediate compound for producing 2-amino-6-(2-substituted-4-phenoxy) substituted pyridine compound | �Ʒ� | 2004-07-28 | — | — | CN | disclosed |
| EP-0958282-B1 | 2-AMINO-6-(2-SUBSTITUTED-4-PHENOXY)-SUBSTITUTED-PYRIDINES | PFIZER PROD INC (US) | 2004-07-21 | — | — | EP | disclosed |
| US-20030162765-A1 | Use in treatment and prevention of central nervous system and other disorders | PFIZER INC. | 2003-08-28 | — | — | US | disclosed |
| US-20010007873-A1 | Compounds such as 4-(6-amino-pyridin-2-yl)-3-methoxyphenol as nitric oxide synthase inhibitors used to treat central nervous system disorders, inflammatory disorders, septic shock, etc... | PFIZER INC. | 2001-07-12 | — | — | US | disclosed |
| CN-1246848-A | 2-amino-6- (2-substituted-4-phenoxy) -substituted pyridines | PFIZER PROD INC (US) | 2000-03-08 | — | — | CN | disclosed |
| EP-0958282-A1 | 2-AMINO-6-(2-SUBSTITUTED-4-PHENOXY)-SUBSTITUTED-PYRIDINES | Pfizer Products Inc. (US) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998034919-A1 | 2-AMINO-6-(2-SUBSTITUTED-4-PHENOXY)-SUBSTITUTED-PYRIDINES | PFIZER PRODUCTS INC. (US) | 1998-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234946-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | S1PR1, S1PR2, S1PR3 | MAOB 3653/4885BCHE 4077/4885KMT2A 2682/4885 |
| US-20010007873-A1 | Compounds such as 4-(6-amino-pyridin-2-yl)-3-methoxyphenol as nitric oxide synthase inhibitors used to treat central nervous system disorders, inflammatory disorders, septic shock, etc... | NOS1, PTGS1, NOS2 | MAOB 255/4885BCHE 386/4885KMT2A 3062/4885 |
| US-20070078184-A1 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | ADRB2, ADRA2A, ADRA1A | MAOB 191/4885BCHE 1374/4885KMT2A 1842/4885 |
| US-11912693-B2 | Compounds for modulating S1P1 activity and methods of using the same | S1PR1, S1PR2, S1PR3 | MAOB 3653/4885BCHE 4077/4885KMT2A 2682/4885 |
| US-20230167081-A1 | 5-AMINO-2-PIPERIDINON-3-YL-1-OXOISOINDOLINE DERIVATIVES FOR DEGRADATION OF IKZF2 DEGRADERS | IKZF1, IKZF3, IKZF2 | MAOB 4646/4885BCHE 4581/4885KMT2A 105/4885 |
| US-20030162765-A1 | Use in treatment and prevention of central nervous system and other disorders | GRIN2C, GRIN2A, CNR2 | MAOB 96/4885BCHE 105/4885KMT2A 1651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.