Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL887659 | 0.71 | TLR7 (0.30) | TLR7 | |
| SCHEMBL2909210 | 0.68 | ABL1 (0.33) | TLR7 | |
| SCHEMBL13211901 | 0.67 | — | — | |
| SCHEMBL2910181 | 0.64 | — | — | |
| SCHEMBL2908006 | 0.62 | TLR7 (0.35) | TLR7 | |
| SCHEMBL887869 | 0.59 | MAPT (0.36) | — | |
| SCHEMBL2908004 | 0.58 | PIK3CD (0.41) | TLR7 | |
| SCHEMBL30552828 | 0.56 | KDM4E (0.35) | TLR7 | |
| SCHEMBL7170269 | 0.55 | NPY5R (0.35) | TLR7 | |
| SCHEMBL2906856 | 0.55 | TLR7 (0.34) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687609-B1 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | EPOCH BIOSCIENCES INC (US) | 2014-12-10 | — | — | EP | disclosed |
| US-7759126-B2 | Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for amplification (or PCR) analysis | ELITECH HOLDING B.V. (NL) | 2010-07-20 | — | — | US | disclosed |
| US-20080293586-A1 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | EPOCH BIOSCIENCES, INC. (US) | 2008-11-27 | — | — | US | disclosed |
| US-7381818-B2 | Fluorescent probes containing 5′-minor groove binder, fluorophore and quenching moieties and methods of use thereof | EPOCH BIOSCIENCES, INC. (US) | 2008-06-03 | — | — | US | disclosed |
| EP-1687609-A2 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | Epoch Biosciences, Inc. (US) | 2006-08-09 | — | — | EP | disclosed |
| US-20050214797-A1 | Fluorescent probes for DNA detection by hybridization with improved sensitivity and low background | EPOCH BIOSCIENCES, INC (US) | 2005-09-29 | — | — | US | disclosed |
| WO-2005043127-A2 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | EPOCH BIOSCIENCES, INC. (US) | 2005-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293586-A1 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | SSBP1, DDB1, DNA2 | TLR7 1911/4885 |
| US-20050214797-A1 | Fluorescent probes for DNA detection by hybridization with improved sensitivity and low background | SSBP1, DDB1, DNA2 | TLR7 1911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.