Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910181 | 0.87 | — | — | |
| SCHEMBL887874 | 0.80 | ABL1 (0.36) | ABL1EGFRSRCPRKCA | |
| SCHEMBL2908004 | 0.78 | PIK3CD (0.41) | ABL1EGFRSRCPRKCATLR7 | |
| SCHEMBL887655 | 0.78 | ABL1 (0.37) | ABL1EGFRSRCPRKCA | |
| SCHEMBL887659 | 0.77 | TLR7 (0.30) | TLR7 | |
| SCHEMBL3418187 | 0.68 | TLR7 (0.30) | TLR7 | |
| SCHEMBL887825 | 0.66 | PIK3CD (0.43) | ABL1EGFRSRCMKNK1MKNK2 | |
| SCHEMBL3424170 | 0.64 | ABL1 (0.41) | ABL1EGFRSRCPRKCA | |
| SCHEMBL28823281 | 0.64 | PNP (0.38) | — | |
| SCHEMBL3417904 | 0.63 | ABL1 (0.40) | ABL1EGFRSRCPRKCAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7715989-B2 | Systems and methods for predicting oligonucleotide melting temperature (TmS) | ELITECH HOLDING B.V. (NL) | 2010-05-11 | — | — | US | claimed |
| US-7553643-B2 | Method for amplifying target nucleic acid sequences using a primer comprising an AP endonuclease-cleavable linker | EPOCH BIOSCIENCES, INC. (US) | 2009-06-30 | — | — | US | claimed |
| US-9085800-B2 | Functionalized 3-alkynyl pyrazolopyrimidine analogues as universal bases and methods of use | ELITECH HOLDING B.V. (NL) | 2015-07-21 | — | — | US | disclosed |
| EP-1430147-B1 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES INC (US) | 2013-05-22 | — | — | EP | disclosed |
| US-20120244535-A1 | FUNCTIONALIZED 3-ALKYNYL PYRAZOLOPYRIMIDINE ANALOGUES AS UNIVERSAL BASES AND METHODS OF USE | ELITECH HOLDING B.V. | 2012-09-27 | — | — | US | disclosed |
| EP-1975256-B1 | Modified oligonucleotides for mismatch discrimination | EPOCH BIOSCIENCES INC (US) | 2012-07-11 | — | — | EP | disclosed |
| EP-1261616-B1 | MODIFIED OLIGONUCLEOTIDES FOR MISMATCH DISCRIMINATION | EPOCH BIOSCIENCES INC (US) | 2010-08-18 | — | — | EP | disclosed |
| US-7751982-B2 | TM leveling methods | ELITECH HOLDING B.V. (NL) | 2010-07-06 | — | — | US | disclosed |
| US-7715989-B2 | Systems and methods for predicting oligonucleotide melting temperature (TmS) | ELITECH HOLDING B.V. (NL) | 2010-05-11 | — | — | US | disclosed |
| EP-1995330-A1 | Modified oligonucleotides for mismatch discrimination | Epoch Biosciences, Inc. (US) | 2008-11-26 | — | — | EP | disclosed |
| EP-1975256-A1 | Modified oligonucleotides for mismatch discrimination | Epoch Biosciences, Inc. (US) | 2008-10-01 | — | — | EP | disclosed |
| EP-1430147-A1 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | Epoch Biosciences, Inc. (US) | 2004-06-23 | — | — | EP | disclosed |
| WO-2002099141-A9 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES INC (US) | 2004-05-27 | — | — | WO | disclosed |
| US-6683173-B2 | CONJUGATING OLIGONUCLEOTIDE WITH 3-SUBSTITUTED PYRAZOLO(3,4-D)PYRIMIDINES AND/OR 5-SUBSTITUTED PYRIMIDINE MINOR GROOVE BINDER | EPOCH BIOSCIENCES, INC. | 2004-01-27 | — | — | US | disclosed |
| US-20030235822-A1 | Systems and methods for predicting oligonucleotide melting temperature (TmS) | EPOCH BIOSCIENCES, INC. | 2003-12-25 | — | — | US | disclosed |
| WO-2003107144-A2 | SYSTEMS AND METHODS FOR PREDICTING OLIGONUCLEOTIDE MELTING TEMPERATURES (TMS) | EPOCH BIOSCIENCES, INC. (US) | 2003-12-24 | — | — | WO | disclosed |
| US-20030224359-A1 | TMLEVELING METHODS | EPOCH BIOSCIENCES, INC. | 2003-12-04 | — | — | US | disclosed |
| WO-2002099141-A1 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES, INC. (US) | 2002-12-12 | — | — | WO | disclosed |
| EP-1261616-A2 | MODIFIED OLIGONUCLEOTIDES FOR MISMATCH DISCRIMINATION | Epoch Biosciences, Inc. (US) | 2002-12-04 | — | — | EP | disclosed |
| WO-2001064958-A2 | MODIFIED OLIGONUCLEOTIDES FOR MISMATCH DISCRIMINATION | EPOCH BIOSCIENECS, INC. (US) | 2001-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120244535-A1 | FUNCTIONALIZED 3-ALKYNYL PYRAZOLOPYRIMIDINE ANALOGUES AS UNIVERSAL BASES AND METHODS OF USE | NUDT1, ADAR, DPYD | ABL1 517/4885EGFR 4332/4885SRC 4734/4885 |
| US-20030224359-A1 | TMLEVELING METHODS | PTBP3, RNGTT, DTYMK | ABL1 2788/4885EGFR 3900/4885SRC 4574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.