SCHEMBL3418340

SCHEMBL3418340

CC(=O)C(=O)O[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO.[NaH]

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PDE4A P27815 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
USP2 O75604 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
KDM4E B2RXH2 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5829662 0.98 LMNA (0.38) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL873892 0.98 LMNA (0.38) LMNAL3MBTL1PDE4ATDP1USP2
Alcohol SCHEMBL15066415 0.95 LMNA (0.35) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL8325036 0.93 LMNA (0.34) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL6573573 0.93 LMNA (0.34) LMNAL3MBTL1PDE4ATDP1USP2
Fructose SCHEMBL11151878 0.88 CYP2C9 (0.34) LMNAL3MBTL1PDE4A
SCHEMBL18341352 0.86 AKR1B1 (0.33)
SCHEMBL17844291 0.86
SCHEMBL2722434 0.85 LMNA (0.35) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL4271266 0.85 LMNA (0.35) LMNAL3MBTL1PDE4ATDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118139969-A Method for rapid infiltration of 3D scaffolds with cells 紫露草公司 2024-06-04 CN disclosed
WO-2010049783-A1 STEM CELLS IN OBSTETRICS AND GYNAECOLOGY PATKI RESEARCH FOUNDATION & HOSPITAL (IN) 2010-05-06 WO disclosed
US-20080305074-A1 Stem cell factor AMGEN INC. (US) 2008-12-11 US disclosed
US-20070071714-A1 Stem cell factor AMGEN INC. (US) 2007-03-29 US disclosed
US-7144731-B2 SCF antibody compositions and methods of using the same AMGEN INC. (US) 2006-12-05 US disclosed
US-20050261175-A1 SCF antibody compositions and methods of using the same BIOVITRUM AB (PUBL) (SE) 2005-11-24 US disclosed
US-6967029-B1 Method for increasing hematopoietic progenitor cells by stem cell factor AMGEN INC. (US) 2005-11-22 US disclosed
US-20050080250-A1 Methods of stimulating growth of stromal cells in a human ZSEBO KRISZTINA M (US) 2005-04-14 US disclosed
US-6852313-B1 Method of stimulating growth of melanocyte cells by administering stem cell factor AMGEN INC. (US) 2005-02-08 US disclosed
US-6841147-B2 Stem cell factor compositions AMGEN, INC. (US) 2005-01-11 US disclosed
US-20040181044-A1 Method of stimulating growth of epithelial cells by administering stem cell factor ZSEBO KRISZTINA M (US) 2004-09-16 US disclosed
US-6759215-B1 FOR TREATING DISORDERS INVOLVING HEMATOPOIETIC CELLS AMGEN INC. 2004-07-06 US disclosed
US-20020031491-A1 STEM CELL FACTOR: COMPOSITION CLAIMS BIOVITRUM AB (PUBL) (SE) 2002-03-14 US disclosed
US-20020018763-A1 A METHOD OF STIMULATING GROWTH OF STROMAL CELLS WITH STEM CELL FACTOR (SCF) POLYPEPTIDES ZSEBO KRISZKINA M (US) 2002-02-14 US disclosed
US-6248319-B1 BLOOD DISORDERS BIOVITRUM AB (PUBL) (SE) 2001-06-19 US disclosed
US-6218148-B1 DNA SEQUENCE OF PROTEIN; RECOMBINANT CULTURE PRODUCTION; REGENERATION OF HEMATOPOIETIC SYSTEM AFTER CHEMOTHERAPY, RADIATION, BLOOD DISORDERS, OR VIRAL DISORDERS SUCH AS ACQUIRED IMMUNE DEFICIENCY SYNDROME AMGEN INC. 2001-04-17 US disclosed
US-6207417-B1 NUCLEOTIDE SEQUENCES FOR THE EXPRESSION OF EXOGENOUS GENES; FOR THE TREATMENT OF BLOOD DISORDERS BIOVITRUM AB (PUBL) (SE) 2001-03-27 US disclosed
US-6207454-B1 EXPOSING TARGET MAMMALIAN CELL THAT EXPRESSES STEM CELL FACTOR RECEPTOR TO ACTIVE STEM CELL FACTOR OR ANALOG, THEN INTRODUCING POLYNUCLEOTIDE TO CELL; GENE THERAPY AMGEN INC. 2001-03-27 US disclosed
US-6207802-B1 NON-HUMAN, MAMMALIAN POLYPEPTIDE OF DEFINED AMINO ACID SEQUENCE WHICH ACTIVATES THE GROWTH OF EARLY HEMATOPOIETIC PROGENITOR CELLS; TREATMENT OF BLOOD DISORDERS; ANTICARCINOGENIC AGENTS; BONE MARROW REGENERATION AMGEN INC. 2001-03-27 US disclosed
US-6204363-B1 POLYPEPTIDE ASSOCIATED WITH CELL PROPAGATION; FOR THE TREATMENT OF CELL PROPAGATION DEFECTS IN CELLS AMGEN INC. 2001-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080305074-A1 Stem cell factor KIT, CBFB, ILF2 LMNA 3723/4885L3MBTL1 1324/4885PDE4A 2273/4885
US-20020031491-A1 STEM CELL FACTOR: COMPOSITION CLAIMS CBFB, KIT, RUNX1 LMNA 2923/4885L3MBTL1 2527/4885PDE4A 2442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.