SCHEMBL873892

SCHEMBL873892

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nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PDE4A P27815 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
USP2 O75604 1/20 0.35
SLCO1B1 Q9Y6L6 1/20 0.35
KDM4E B2RXH2 2/20 0.33
AKR1B1 P15121 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5829662 1.00 LMNA (0.38) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL3418340 0.98 LMNA (0.37) LMNAL3MBTL1PDE4ATDP1USP2
Alcohol SCHEMBL15066415 0.97 LMNA (0.35) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL8325036 0.95 LMNA (0.34) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL6573573 0.95 LMNA (0.34) LMNAL3MBTL1PDE4ATDP1USP2
Fructose SCHEMBL11151878 0.90 CYP2C9 (0.34) LMNAL3MBTL1PDE4A
SCHEMBL18341352 0.87 AKR1B1 (0.33) AKR1B1
SCHEMBL17844291 0.87
SCHEMBL2722434 0.87 LMNA (0.35) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL4274437 0.87 LMNA (0.35) LMNAL3MBTL1PDE4ATDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250241957-A1 INTRA-ERYTHROCYTE DEXAMETHASONE FOR TREATMENT OF ATAXIA-TELANGIECTASIA QUINCE THERAPEUTICS S.P.A. (IT) 2025-07-31 US claimed
US-12311059-B2 Process for the preparation of erythrocytes loaded with one or more substances of pharmaceutical interest and so obtained erythrocytes QUINCE THERAPEUTICS S.P.A. (IT) 2025-05-27 US claimed
US-20060281159-A1 Method for sustained microbial production of hydrogen gas in a bioreactor DIZ HARRY R 2006-12-14 US claimed
US-5076273-A Collecting a body fluid in dermal concentration patch; complexing analyte with immobilized binding partner; perspiration; non-invasive SUDOR PARTNERS (US) 1991-12-31 US claimed
CN-122038274-A Method for inducing differentiation and maturation of alveolar organoids and application thereof 广州国家实验室 2026-05-15 CN disclosed
CN-122038284-A Method for inducing differentiation of anterior foregut endoderm cells to form lung progenitor cells and application thereof 广州国家实验室 2026-05-15 CN disclosed
US-20260130895-A1 METABOLISM ENHANCING COMPOSITIONS Red Mountain Med Spa, LLC (US) 2026-05-14 US disclosed
EP-4281538-B1 APPARATUS, SYSTEMS, AND METHODS FOR PREPARING AN OUTPUT SAMPLE WITH AERATION AVAILS MED INC (US) 2026-04-22 EP disclosed
US-12551470-B2 Metabolism enhancing compositions Red Mountain Med Spa, LLC (US) 2026-02-17 US disclosed
US-12522854-B2 Systems, devices and methods for determining most probable number in biological sample analysis ANCERA, INC. (US) 2026-01-13 US disclosed
EP-4350323-B1 METHODS FOR PREPARING AN OUTPUT SAMPLE COMPRISING A DEFINED CONCENTRATION OF AN INFECTIOUS AGENT FOR DOWNSTREAM TESTING AVAILS MED INC (US) 2025-12-03 EP disclosed
US-20250325702-A1 COMPOSITIONS AND METHODS FOR EDITING A TRANSTHYRETIN GENE BEAM THERAPEUTICS INC. (US) 2025-10-23 US disclosed
WO-1998051277-A1 MEDICAL USES OF PYRUVATES CASE WESTERN RESERVE UNIVERSITY (US) 1998-11-19 WO disclosed
EP-0543867-B1 METHOD AND APPARATUS FOR DETERMINATION OF CHEMICAL SPECIES IN BODY FLUID SUDOR PARTNERS (US) 1996-05-01 EP disclosed
EP-0433382-B1 METHOD AND APPARATUS FOR CHEMICAL SPECIES DETERMINATION SCHOENDORFER DONALD W (US) 1995-11-08 EP disclosed
WO-1992021234-A1 COMPOSITION AND METHOD FOR CULTURING AND FREEZING CELLS AND TISSUES VETREPHARM, INC. (CA) 1992-12-10 WO disclosed
EP-0337003-B1 USE OF FRUCTOSE-1,6-DIPHOSPHATE IN THE TREATMENT OF ACUTE ALCOHOLIC INTOXICATION AND CHRONIC ETHYLISM, AND RELATED PHARMACEUTICAL COMPOSITIONS BIOMEDICA FOSCAMA INDUSTRIA CHIMICO-FARMACEUTICA S.P.A. (IT) 1992-09-30 EP disclosed
US-5102783-A Using hyaluronic acid acid VETREPHARM, INC. (CA) 1992-04-07 US disclosed
EP-0337003-A2 Use of fructose-1,6-diphosphate in the treatment of acute alcoholic intoxication and chronic ethylism, and related pharmaceutical compositions BIOMEDICA FOSCAMA INDUSTRIA CHIMICO-FARMACEUTICA S.P.A. (IT) 1989-10-18 EP disclosed
US-4870057-A Use of fructose-1,6-diphosphate in the treatment of acute alcoholic intoxication and chronic ethylism, and related pharmaceutical compositions BIOMEDICA FOSCAMA INDUSTRIA CHIMICO-FARMACEUTICA S.P.A. (IT) 1989-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325702-A1 COMPOSITIONS AND METHODS FOR EDITING A TRANSTHYRETIN GENE TTR, TTN, HTT LMNA 81/4885L3MBTL1 413/4885PDE4A 3522/4885
US-20260130895-A1 METABOLISM ENHANCING COMPOSITIONS GYS2, SLC19A1, SLC19A2 LMNA 1425/4885L3MBTL1 2259/4885PDE4A 2639/4885
US-12551470-B2 Metabolism enhancing compositions BHMT, SLC19A2, GYS2 LMNA 1513/4885L3MBTL1 1677/4885PDE4A 2363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.