SCHEMBL3418351

SCHEMBL3418351

CC(C)(C)c1ccc2cc3ccc(C(C)(C)C)cc3cc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
HPGD P15428 2/20 0.48
ALOX15 P16050 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
TSHR P16473 1/20 0.43
MAPT P10636 3/20 0.43
MEN1 O00255 1/20 0.43
GAA P10253 1/20 0.43
PKM P14618 1/20 0.43
RECQL P46063 1/20 0.43
KMT2A Q03164 1/20 0.43
LMNA P02545 1/20 0.42
TYR P14679 1/20 0.42
NR1I2 O75469 1/20 0.42
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
PLA2G1B P04054 1/20 0.40
NFKB1 P19838 1/20 0.40
CASP3 P42574 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29438049 1.00 ALDH1A1 (0.48) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL29447635 1.00 ALDH1A1 (0.48) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL983124 1.00 ALDH1A1 (0.48) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL29438045 1.00 ALDH1A1 (0.48) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL30010382 0.94 ALDH1A1 (0.52) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL348347 0.94 ALDH1A1 (0.52) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL29416694 0.93 ALDH1A1 (0.45) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL260748 0.93 ALDH1A1 (0.45) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL7521505 0.92 ALDH1A1 (0.50) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL30010643 0.92 ALDH1A1 (0.50) ALDH1A1HPGDALOX15HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3898725-B1 HETEROCYCLE-HETEROCYCLE-BASED GROUP IV TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2025-10-01 EP disclosed
US-12252573-B2 Heterocycle-heterocycle-based group IV transition metal catalysts for olefin polymerization DOW GLOBAL TECHNOLOGIES LLC (US) 2025-03-18 US disclosed
US-12122798-B2 Perchlorinated disilenes and germasilenes and also neopentatetrelanes, a method for the preparation thereof and use thereof EVONIK OPERATIONS GMBH (DE) 2024-10-22 US disclosed
US-12104002-B2 Monobidentate aminopyridine group IV transition metal olefin copolymerization catalysts with ultra-high molecular weight capability and ultra-low comonomer incorporation DOW GLOBAL TECHNOLOGIES LLC (US) 2024-10-01 US disclosed
CN-113597438-B Mono-dentate aminopyridine IV group transition metal olefin copolymerization catalyst with ultra-high molecular weight capability and ultra-low comonomer combination 陶氏环球技术有限责任公司 2024-02-13 CN disclosed
EP-3947481-B1 MONOBIDENTATE AMINOPYRIDINE GROUP IV TRANSITION METAL OLEFIN COPOLYMERIZATION CATALYSTS WITH ULTRA-HIGH MOLECULAR WEIGHT CAPABILITY AND ULTRA-LOW COMONOMER INCORPORATION DOW GLOBAL TECHNOLOGIES LLC (US) 2023-08-30 EP disclosed
CN-116554370-A Metallocene catalyst, preparation method and application thereof 万华化学集团股份有限公司 2023-08-08 CN disclosed
US-20220162354-A1 MONOBIDENTATE AMINOPYRIDINE GROUP IV TRANSITION METAL OLEFIN COPOLYMERIZATION CATALYSTS WITH ULTRA-HIGH MOLECULAR WEIGHT CAPABILITY AND ULTRA-LOW COMONOMER INCORPORATION DOW GLOBAL TECHNOLOGIES LLC (US) 2022-05-26 US disclosed
US-20220056164-A1 HETEROCYCLE-HETEROCYCLE-BASED GROUP IV TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2022-02-24 US disclosed
EP-3947481-A1 MONOBIDENTATE AMINOPYRIDINE GROUP IV TRANSITION METAL OLEFIN COPOLYMERIZATION CATALYSTS WITH ULTRA-HIGH MOLECULAR WEIGHT CAPABILITY AND ULTRA-LOW COMONOMER INCORPORATION Dow Global Technologies LLC (US) 2022-02-09 EP disclosed
CN-111233701-B Benzobucket alkene pentapterene ligand, transition metal catalyst, preparation method and application in ethylene polymerization 中国科学院长春应用化学研究所 2021-03-23 CN disclosed
WO-2020197907-A1 MONOBIDENTATE AMINOPYRIDINE GROUP IV TRANSITION METAL OLEFIN COPOLYMERIZATION CATALYSTS WITH ULTRA-HIGH MOLECULAR WEIGHT CAPABILITY AND ULTRA-LOW COMONOMER INCORPORATION DOW GLOBAL TECHNOLOGIES LLC (US) 2020-10-01 WO disclosed
WO-2020132422-A1 HETEROCYCLE-HETEROCYCLE-BASED GROUP IV TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2020-06-25 WO disclosed
CN-111233701-A Novel benzo bucket alkene pentapterene ligand, transition metal catalyst, preparation method and application in ethylene polymerization 中国科学院长春应用化学研究所 2020-06-05 CN disclosed
CN-107973900-A A kind of poly- anthracene compound and its preparation method and application 华南理工大学 2018-05-01 CN disclosed
US-7670506-B1 Photoactive compositions for liquid deposition E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-03-02 US disclosed
US-5494944-A BLEND OF MATERIAL POLYMERIZABLE BY FREE RADICAL CATALYSTAND AN IRON COMPOUND CIBA-GEIGY CORPORATION (US) 1996-02-27 US disclosed
US-5371115-A Having sensitizers, electron acceptors selected from peracids, hydroperoxides and quinones; photosensitive, photoresists CIBA-GEIGY CORPORATION (US) 1994-12-06 US disclosed
EP-0152377-B1 CURABLE COMPOSITIONS AND THEIR USE CIBA-GEIGY AG (CH) 1987-12-09 EP disclosed
EP-0152377-A2 Curable compositions and their use CIBA-GEIGY AG (CH) 1985-08-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12122798-B2 Perchlorinated disilenes and germasilenes and also neopentatetrelanes, a method for the preparation thereof and use thereof DDT, DHPS, CD99 ALDH1A1 1373/4885HPGD 1262/4885ALOX15 2737/4885
US-12252573-B2 Heterocycle-heterocycle-based group IV transition metal catalysts for olefin polymerization MCM4, CCNI, CDK4 ALDH1A1 1041/4885HPGD 98/4885ALOX15 101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.