Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.38 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.38 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.38 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.38 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | RAD52 | P43351 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3419365 | 1.00 | HTT (0.38) | HTTSMN1; SMN2KMT2AHSP90AA1LMNA | |
| SCHEMBL9067234 | 0.98 | KMT2A (0.39) | HTTSMN1; SMN2KMT2AHSP90AA1LMNA | |
| SCHEMBL15657208 | 0.98 | KMT2A (0.39) | HTTSMN1; SMN2KMT2AHSP90AA1LMNA | |
| Iodide SCHEMBL810561 | 0.97 | HTT (0.41) | HTTSMN1; SMN2KMT2AHSP90AA1LMNA | |
| Hydrochloric Acid SCHEMBL3419607 | 0.97 | SMN1; SMN2 (0.38) | HTTSMN1; SMN2KMT2AHSP90AA1LMNA | |
| Hydrochloric Acid SCHEMBL8415719 | 0.97 | SMN1; SMN2 (0.38) | HTTSMN1; SMN2KMT2AHSP90AA1LMNA | |
| Bromide SCHEMBL12500813 | 0.93 | ALDH1A1 (0.31) | TSHRCA1CA2ALDH1A1 | |
| SCHEMBL29390 | 0.91 | ALDH1A1 (0.32) | HTTSMN1; SMN2KMT2AHSP90AA1LMNA | |
| Hydrochloric Acid SCHEMBL29697222 | 0.90 | ALDH1A1 (0.31) | TSHRCA1CA2ALDH1A1 | |
| Sulfuric Acid SCHEMBL30240028 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017563-A1 | POLYMERIC IONIC LIQUIDS, METHODS OF MAKING AND METHODS OF USE THEREOF | UNIVERSITY OF TOLEDO (US) | 2010-02-11 | — | — | WO | claimed |
| WO-2013181345-A2 | SYNTHESIS OF POLYMERIC IONIC LIQUIDS USING A PHOTOCHEMICAL POLYMERIZATION PROCESS | THE UNIVERSITY OF TOLEDO (US) | 2013-12-05 | — | — | WO | disclosed |
| WO-2010017563-A1 | POLYMERIC IONIC LIQUIDS, METHODS OF MAKING AND METHODS OF USE THEREOF | UNIVERSITY OF TOLEDO (US) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010017564-A1 | BORON SELECTIVE IONIC LIQUIDS AND POLYMERIC IONIC LIQUIDS, METHODS OF MAKING AND METHODS OF USE THEREOF | UNIVERSITY OF TOLEDO (US) | 2010-02-11 | — | — | WO | disclosed |