Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.35 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.35 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | RAD52 | P43351 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15657208 | 0.98 | KMT2A (0.39) | HTTSMN1; SMN2KMT2AKDM4ENPC1 | |
| SCHEMBL9067234 | 0.98 | KMT2A (0.39) | HTTSMN1; SMN2KMT2AKDM4ENPC1 | |
| Bromide SCHEMBL3418571 | 0.97 | HTT (0.38) | HTTSMN1; SMN2KMT2AKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL3419607 | 0.97 | SMN1; SMN2 (0.38) | HTTSMN1; SMN2KMT2AKDM4ENPC1 | |
| Bromide SCHEMBL3419365 | 0.97 | HTT (0.38) | HTTSMN1; SMN2KMT2AKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL8415719 | 0.97 | SMN1; SMN2 (0.38) | HTTSMN1; SMN2KMT2AKDM4ENPC1 | |
| SCHEMBL29390 | 0.91 | ALDH1A1 (0.32) | HTTSMN1; SMN2KMT2AKDM4ENPC1 | |
| Bromide SCHEMBL12500813 | 0.90 | ALDH1A1 (0.31) | ALDH1A1CA1CA2TSHR | |
| Hydrochloric Acid SCHEMBL29697222 | 0.90 | ALDH1A1 (0.31) | ALDH1A1CA1CA2TSHR | |
| Sulfuric Acid SCHEMBL30240028 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9345811-B2 | Medical antimicrobial composition and medical device comprising the same | TORAY INDUSTRIES, INC. (JP) | 2016-05-24 | — | — | US | disclosed |
| EP-2275154-B1 | ANTIBACTERIAL COMPOSITION FOR MEDICAL USE AND MEDICAL DEVICE | TORAY INDUSTRIES (JP) | 2015-07-01 | — | — | EP | disclosed |
| US-20140120146-A1 | MEDICAL ANTIMICROBIAL COMPOSITION AND MEDICAL DEVICE COMPRISING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2014-05-01 | — | — | US | disclosed |
| US-8652499-B2 | Medical antimicrobial composition and medical device comprising the same | TORAY INDUSTRIES, INC. (JP) | 2014-02-18 | — | — | US | disclosed |
| EP-2275154-A1 | ANTIBACTERIAL COMPOSITION FOR MEDICAL USE AND MEDICAL DEVICE | Toray Industries, Inc. (JP) | 2011-01-19 | — | — | EP | disclosed |
| US-20110008403-A1 | MEDICAL ANTIMICROBIAL COMPOSITION AND MEDICAL DEVICE COMPRISING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110008403-A1 | MEDICAL ANTIMICROBIAL COMPOSITION AND MEDICAL DEVICE COMPRISING THE SAME | AAAS, MMS19, MSN | CHRM1 4443/4885ACHE 2781/4885CHRM3 4135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.